Rönning O, Peltomäki T
Institute of Dentistry, University of Turku, Finland.
Arch Oral Biol. 1991;36(3):203-10. doi: 10.1016/0003-9969(91)90087-b.
The mandibular condyle of 5-, 10- or 20-day inbred male rats was transplanted across the interparietal suture of male litter-mates and the transverse dimension of the neurocranium was measured from dry skulls at 25 or 35 days. The width of the neurocranium had increased significantly from days 5 or 10 to 25 in the rats with the transplants, whereas the difference from controls was small or non-existent by 35 days. Histological examination showed that the cartilaginous zone was reduced in the transplants at 25 days but that there were still layers of chondrocytes at 35 days. It is suggested that the rat mandibular condyle is endowed with a tissue-separating, interstitial growth potential that, to some extent, is unrelated to mobility, and essentially effected by chondrocyte hypertrophy.
将5日龄、10日龄或20日龄近交系雄性大鼠的下颌髁突移植到同窝雄性大鼠的顶间缝处，并在25天或35天时从干燥颅骨测量神经颅骨的横向尺寸。移植大鼠的神经颅骨宽度从5天或10天到25天显著增加，而到35天时与对照组的差异很小或不存在。组织学检查显示，25天时移植组织中的软骨区减少，但35天时仍有软骨细胞层。研究表明，大鼠下颌髁突具有组织分离的间质生长潜能，在一定程度上与活动能力无关，且主要受软骨细胞肥大影响。
