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骶骨神经鞘瘤的治疗:4例报告并文献复习

The management of sacral schwannoma: report of four cases and review of literature.

作者信息

Chandhanayingyong Chandhanarat, Asavamongkolkul Apichat, Lektrakul Nittaya, Muangsomboon Sorranart

机构信息

Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Prannok road, Bangkoknoi, Bangkok 10700, Thailand.

出版信息

Sarcoma. 2008;2008:845132. doi: 10.1155/2008/845132.

Abstract

Sacral schwannoma is a rare retrorectal tumor in adults. Postoperative sacral neurological deficit is difficult to avoid. Currently, there is no established consensus regarding best treatment options. We present the management and outcomes of sacral schwannoma in 4 patients treated with intralesional curettage and postoperative radiation. There were 3 women and one man (average age: 45.5 years) with long duration of lumbosacral pain with or without radiculopathy. Intralesional curettage was performed by posterior approach and adjuvant radiation therapy with dosage of 5000-6600 cGy was given after surgery. The mean follow-up time was 18 months (range 4-23 months). Symptoms of radiculopathy had decreased in all patients. The recent radiographic findings show evidence of sclerosis at the sacrum one year postoperatively, but the size was unchanged. Intralesional curettage and adjuvant radiation therapy can be used in the treatment of sacral schwannoma to relieve symptoms and preserve neurological function.

摘要

骶骨神经鞘瘤是成人罕见的直肠后肿瘤。术后骶神经功能缺损难以避免。目前,关于最佳治疗方案尚无既定共识。我们介绍了4例采用病灶内刮除术和术后放疗治疗的骶骨神经鞘瘤患者的治疗情况及结果。有3名女性和1名男性(平均年龄:45.5岁),存在长期腰骶部疼痛,伴或不伴有神经根病。通过后路进行病灶内刮除术,并在术后给予剂量为5000 - 6600 cGy的辅助放疗。平均随访时间为18个月(范围4 - 23个月)。所有患者的神经根病症状均有所减轻。近期影像学检查结果显示术后1年骶骨有硬化迹象,但大小未变。病灶内刮除术和辅助放疗可用于骶骨神经鞘瘤的治疗,以缓解症状并保留神经功能。

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