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巨大骶部神经鞘瘤:六例报告。

Giant sacral schwannoma: a report of six cases.

机构信息

Department of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Sendai, Japan.

出版信息

Ups J Med Sci. 2010 May;115(2):146-52. doi: 10.3109/03009730903359674.

Abstract

Sacral and presacral schwannomas are often found incidentally, because they present with vague symptoms or symptomless. Schwannoma occurring in this area occasionally presents with enormous dimensions, known as a giant schwannoma. The tumor removal is a surgical challenge due to the difficult approach and abundant vascularity. The aim of this study is to review cases of giant sacral schwannomas focusing the surgical management and outcome. Six patients with sacral and presacral schwannoma were treated surgically. The patients included two males and four females, and the mean age was 47.8 years. All patients experienced pain at the time of presentation. The tumors were classified as intraosseous type in one case, dumb-bell type in four cases, and retroperitoneal type in one case. The tumors were removed with a piecemeal subtotal excision in three patients, a partial excision in two patients, and enucleation in one patient. The surgeries were performed by the combination of an anterior and posterior approach in three patients, a posterior approach in two patients, and an anterior approach in one patient. The mean surgical time was 7.8 hrs, and the mean blood loss was 2572 g. The tumor recurred in one patient after the partial excision and was removed completely in a second surgery. No patient, including the patient who underwent the second surgery, presented with pain and obvious neurological deficit at the final follow-up. The surgical treatment of the giant sacral schwannoma with a piecemeal subtotal excision can achieve a good outcome, avoiding unnecessary neurological deficit.

摘要

骶骨和骶前神经鞘瘤通常是偶然发现的,因为它们表现出模糊的症状或无症状。发生在这个区域的神经鞘瘤偶尔会出现巨大的尺寸,被称为巨大神经鞘瘤。由于手术入路困难和血管丰富,肿瘤切除是一项具有挑战性的手术。本研究旨在回顾巨大骶骨神经鞘瘤的病例,重点讨论手术治疗和结果。六例骶骨和骶前神经鞘瘤患者接受了手术治疗。患者包括 2 名男性和 4 名女性,平均年龄为 47.8 岁。所有患者在就诊时均有疼痛。肿瘤在 1 例为骨内型,4 例为哑铃型,1 例为腹膜后型。3 例采用分块次全切除术切除肿瘤,2 例采用部分切除术切除肿瘤,1 例采用囊内切除术切除肿瘤。3 例患者采用前路和后路联合手术,2 例患者采用后路手术,1 例患者采用前路手术。手术平均时间为 7.8 小时,平均失血量为 2572 克。1 例部分切除后肿瘤复发,再次手术完全切除。包括再次手术的患者在内,所有患者在最终随访时均无疼痛和明显的神经功能缺损。采用分块次全切除术治疗巨大骶骨神经鞘瘤可获得良好的效果,避免不必要的神经功能缺损。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dfb/2853793/8acb7a58e06c/UPS-0300-9734-115-146-g001.jpg

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