果蝇（Drosophila ananassae）嵌合基因“塞壬”（siren）中的氨基酸进化模式与其他源自乙醇脱氢酶（Adh）的嵌合体的模式相似。
Patterns of amino acid evolution in the Drosophila ananassae chimeric gene, siren, parallel those of other Adh-derived chimeras.
作者信息
Shih Hung-Jui, Jones Corbin D
机构信息
Department of Biology and Carolina Center for the Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599-3280, USA.
出版信息
Genetics. 2008 Oct;180(2):1261-3. doi: 10.1534/genetics.108.090068. Epub 2008 Sep 9.
Abstract
siren1 and siren2 are novel alcohol dehydrogenase (Adh)-derived chimeric genes in the Drosophila bipectinata complex. D. ananassae, however, harbors a single homolog of these genes. Like other Adh-derived chimeric genes, siren evolved adaptively shortly after it was formed. These changes likely shifted the catalytic activity of siren.
摘要
siren1和siren2是果蝇双栉果蝇复合体中新型的源自乙醇脱氢酶（Adh）的嵌合基因。然而，拟果蝇仅含有这些基因的一个同源物。与其他源自Adh的嵌合基因一样，siren在形成后不久就发生了适应性进化。这些变化可能改变了siren的催化活性。
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