Wang Gang, Cheng Qi, Zhang Shi, Bai Li, Zeng Jie, Cui Pei-Jing, Zhang Ting, Sun Zhi-Kun, Ren Ru-Jing, Deng Yu-Lei, Xu Wei, Wang Ying, Chen Sheng-Di
Department of Neurology & Institute of Neurology, Ruijin Hospital affiliated with the Medical School of Shanghai Jiaotong University, Shanghai, China.
J Alzheimers Dis. 2008 Sep;15(1):109-15. doi: 10.3233/jad-2008-15109.
The main objective of this study was to assess the economic cost of Alzheimer's disease (AD) in Shanghai, China, as a pilot study for future evaluations. Sixty-seven patients with AD were interviewed, and the information of the AD-related cost and resources used was collected from October 2005 to September 2006. By retrospective analysis, annual costs were calculated and expressed in Chinese renminbi (RMB). Direct cost per patient per year averaged approximately 8,432 RMB (1,058 USD), indirect cost per patient per year was 10,568 RMB (1,326 USD), and annual costs were 19,001 RMB (2,384 USD) per patient per year in this investigation. Total cost was significantly associated with the degree of severity including cognitive function (MMSE) and activity of daily living (ADL). With the increase in the number of persons at risk for developing AD, the economic burden of AD patients in China is significantly heavy.
本研究的主要目的是评估中国上海阿尔茨海默病（AD）的经济成本，作为未来评估的一项试点研究。对67例AD患者进行了访谈，并收集了2005年10月至2006年9月期间与AD相关的成本和资源使用信息。通过回顾性分析，计算出年度成本并用人民币（RMB）表示。本调查中每位患者每年的直接成本平均约为8432元人民币（1058美元），间接成本为10568元人民币（1326美元），每年每位患者的成本为19001元人民币（2384美元）。总成本与严重程度显著相关，包括认知功能（MMSE）和日常生活活动能力（ADL）。随着AD发病风险人群数量的增加，中国AD患者的经济负担显著加重。
