在使用228 ppm氟化物漱口水后，钙预冲洗可显著增加夜间唾液中的氟化物含量。
Calcium pre-rinse greatly increases overnight salivary fluoride after a 228 ppm fluoride rinse.
作者信息
Vogel G L, Chow L C, Carey C M
机构信息
American Dental Association Foundation, Paffenbarger Research Center, Gaithersburg, MD 20899-8546, USA.
出版信息
Caries Res. 2008;42(5):401-4. doi: 10.1159/000154786. Epub 2008 Sep 10.
BACKGROUND
Large increases in salivary fluoride were reported 1 h after a calcium pre-rinse/NaF rinse.
AIMS
This study examined the persistence of these increases.
METHODS
12 subjects rinsed in the evening with water, with a 228 microg/g (ppm) F rinse or with 150 mmol/l calcium lactate followed by a 228 microg/g F rinse. In a second experiment these same patients rinsed with a 912 microg/g F rinse. Saliva samples were obtained the morning after rinsing, centrifuged and the supernatants analyzed.
RESULTS
The Ca pre-rinse/228 microg/g F rinse induced an increase in overnight salivary F over the 912 microg/g F rinse (approximately 2.5 times) and a statistically significant increase over the 228 mug/g F rinse (approximately 5.5 times).
CONCLUSIONS
The results suggest that a Ca pretreatment may increase the cariostatic effect of topical F agents.
背景
据报道，在进行钙预冲洗/氟化钠冲洗1小时后，唾液氟化物大幅增加。
目的
本研究检测了这些增加的持续性。
方法
12名受试者在晚上用水、228微克/克（ppm）的氟冲洗液或150毫摩尔/升乳酸钙冲洗，随后再用228微克/克的氟冲洗液冲洗。在第二个实验中，这些相同的患者用912微克/克的氟冲洗液冲洗。冲洗后次日早晨采集唾液样本，离心后分析上清液。
结果
钙预冲洗/228微克/克氟冲洗液导致过夜唾液氟含量比912微克/克氟冲洗液增加（约2.5倍），且比228微克/克氟冲洗液有统计学显著增加（约5.5倍）。
结论
结果表明，钙预处理可能会增强局部用氟剂的防龋效果。
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