Oke Muse, Ching Rosalind Tan Yan, Carter Lester G, Johnson Kenneth A, Liu Huanting, McMahon Stephen A, White Malcolm F, Bloch Carlos, Botting Catherine H, Walsh Martin A, Latiff Aishah A, Kennedy Malcolm W, Cooper Alan, Naismith James H
Centre for Biomolecular Science and The Scottish Structural Proteomics Facility, The University, St Andrews, UK.
Angew Chem Int Ed Engl. 2008;47(41):7853-6. doi: 10.1002/anie.200802901.
Ranasmurfin is an unusual blue protein isolated from the nests of a Malaysian tree frog, Polypedates leucomystax,[1] showing the rich chemical diversity displayed by biomolecular foams. Many species of tropical frogs use foams to protect delicate eggs and developing embryos against environmental challenges. These nests act as miniature ecosystems containing a spectrum of novel proteins and other macromolecules with functions related to foam stabilization and adhesion, resistance to microbial degradation, predation, or dehydration, providing a biocompatible environment for embryonic development.Thisworkformspartofourwiderstudyofthe intriguing physical and chemical properties of biofoams as unusual examples of biological soft matter.[2]
雨蛙精蛋白是一种从马来西亚树蛙白颌大角蟾的巢穴中分离出的特殊蓝色蛋白质,[1] 展现了生物分子泡沫所具有的丰富化学多样性。许多热带蛙类利用泡沫来保护脆弱的卵和发育中的胚胎免受环境挑战。这些巢穴充当着微型生态系统,含有一系列与泡沫稳定和黏附、抗微生物降解、抵御捕食或脱水相关功能的新型蛋白质和其他大分子,为胚胎发育提供了生物相容性环境。这项工作是我们对生物泡沫作为生物软物质特殊实例的有趣物理和化学性质进行更广泛研究的一部分。[2]