Mulligan R, Seirawan H, Alves M E, Navazesh M, Phelan J A, Greenspan D, Greenspan J S, Mack W J
School of Dentistry, University of Southern California, Los Angeles, CA, USA.
Community Dent Oral Epidemiol. 2008 Dec;36(6):549-57. doi: 10.1111/j.1600-0528.2008.00443.x. Epub 2008 Sep 8.
Objective measures of dental diseases reflect only their clinical end-point. There is a need to use multidimensional measures of diseases that consider their psychosocial aspects and functional impact. The aim of this study is to compare the oral health-related quality of life (OHRQOL) between a group of HIV-infected women and a similar group of at-risk HIV-uninfected women, and to investigate the role of potential confounding clinical oral health and behavioral factors.
Our sample included HIV-infected women (87%) and women at risk for HIV infection (13%) followed up for 5.5 years. OHRQOL was measured using the short version of the Oral Health Impact Profile (OHIP-14), which is a validated and reliable instrument.
HIV-infected women averaged 10% poorer OHRQOL than HIV-uninfected women; this difference was not apparent after adjusting for the number of study visits attended and significant behavioral and clinical oral health factors. The OHRQOL was inversely related to dental and periodontal diseases and to smoking and freebase cocaine use; these relationships were not confounded by HIV status.
The study identified specific clinical and behavioral factors where dental professionals can intervene to possibly improve the OHRQOL of HIV-infected or at-risk HIV-uninfected women.
牙科疾病的客观测量仅反映其临床终点。有必要使用考虑到心理社会方面和功能影响的多维疾病测量方法。本研究的目的是比较一组感染艾滋病毒的女性和一组类似的有感染艾滋病毒风险的未感染女性的口腔健康相关生活质量(OHRQOL),并调查潜在的混杂临床口腔健康和行为因素的作用。
我们的样本包括感染艾滋病毒的女性(87%)和有感染艾滋病毒风险的女性(13%),随访时间为5.5年。使用口腔健康影响程度量表简版(OHIP - 14)测量OHRQOL,这是一种经过验证且可靠的工具。
感染艾滋病毒的女性的OHRQOL平均比未感染艾滋病毒的女性差10%;在对参加研究访视的次数以及重要的行为和临床口腔健康因素进行调整后,这种差异并不明显。OHRQOL与牙齿和牙周疾病以及吸烟和使用游离碱可卡因呈负相关;这些关系不受艾滋病毒感染状况的影响。
该研究确定了牙科专业人员可以进行干预的特定临床和行为因素,有可能改善感染艾滋病毒或有感染艾滋病毒风险的未感染女性的OHRQOL。