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早产婴儿母亲孕期使用非法药物的情况。

The use of illicit drugs during pregnancy among mothers of premature infants.

作者信息

Vélez Nydia M, García Inés E, García Lourdes, Valcárcel Marta

机构信息

UPR School of Medicine, Department of Pediatrics, Neonatology Section, San Juan, PR 00936-5067.

出版信息

P R Health Sci J. 2008 Sep;27(3):209-12.

Abstract

BACKGROUND

Tobacco, alcohol and/or illicit drug use during pregnancy are risk factors for neonatal complications. In Puerto Rico, the Department of Health reports that 32% of pregnant women use alcohol and 3% use illicit drugs. Nineteen percent (19.1%) of newborns are born prematurely. The purpose of this study is to determine the prevalence of illicit drug use during pregnancy in mothers of premature infants.

METHODS

This study included the data of 218 mothers of premature infants admitted to the Neonatal Intensive Care Unit of the University Pediatric Hospital during 2002 to 2005 enrolled in an educational program.

RESULTS

Fourteen women (6%) reported using illicit drugs during pregnancy (cocaine 2%, marihuana 3%, heroin 2%, methadone 2%, and ecstasy 1%). Mothers using drugs during pregnancy were more likely to start prenatal care after the first trimester (21% vs. 10% in nonusers; p < 0.01) and to smoke cigarettes (36% vs. 8% in nonusers; p < 0.01).

CONCLUSIONS

The most important maternal-prenatal risk factor for drug use in this group of mothers, was failure to receive prenatal care during the first trimester, and cigarette use. The use of illicit drugs during pregnancy complicated by a premature delivery is underestimated and many times unknown to physicians. The physicians should be assertive in gathering this information while interviewing women during pregnancy and in the postpartum period since women who use drugs during pregnancy are at higher risk of social problems, future preterm deliveries and may impair adequate follow up of their premature babies.

摘要

背景

孕期吸烟、饮酒和/或使用非法药物是新生儿并发症的危险因素。在波多黎各,卫生部报告称32%的孕妇饮酒,3%使用非法药物。19%(19.1%)的新生儿早产。本研究的目的是确定早产婴儿母亲孕期使用非法药物的患病率。

方法

本研究纳入了2002年至2005年期间入住大学儿科医院新生儿重症监护病房并参加一项教育项目的218名早产婴儿母亲的数据。

结果

14名女性(6%)报告在孕期使用非法药物(可卡因2%、大麻3%、海洛因2%、美沙酮2%、摇头丸1%)。孕期使用药物的母亲更有可能在孕早期之后开始产前护理(使用者为21%,非使用者为10%;p<0.01),且更有可能吸烟(使用者为36%,非使用者为8%;p<0.01)。

结论

在这组母亲中,孕期使用药物最重要的产前危险因素是孕早期未接受产前护理以及吸烟。孕期使用非法药物并发早产的情况被低估,而且医生很多时候并不知晓。医生在孕期和产后对女性进行问诊时应果断收集此类信息,因为孕期使用药物的女性面临更高的社会问题风险、未来早产风险,且可能影响对其早产婴儿的充分随访。

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