J Orthop Sports Phys Ther. 1991;13(6):310-5. doi: 10.2519/jospt.1991.13.6.310.
Supported in part by a North Carolina Physical Therapy Association Student Research Grant. The purpose of this study was to determine whether there were differences in the amount of muscle soreness and serum creatine kinase (CK) produced when ratios of electrically induced muscle contraction time to rest time were varied. Fifteen subjects were randomly assigned to one of three groups, each receiving 10, 15-second electrically induced isometric contractions of the quadriceps femoris muscle with rest periods of 10, 30, and 50 seconds between contractions, respectively. The intensity of the contractions were maintained at 30 percent of an individual's maximum voluntary isometric contraction (MVC). Blood samples for serum CK activity, an indicator of muscle damage, and perceived soreness were collected pretreatment, 24, 48, and 72 hours following the single treatment session. Significant increases in the serum CK and perceived soreness ratings were observed in all groups. Postexercise serum CK increases were found to be significantly different between the 10 seconds and the 30-seconds and 50-seconds rest period groups. Clinically, muscle soreness may result from initial trials of neuromuscular electrical stimulation (NMES) with peak amplitudes sufficient to produce contractions equivalent to 30 percent of the MVC. Contraction time to rest ratios of NMES may influence the amount of muscle damage produced. J Orthop Sports Phys Ther 1991,13(6):310-315.
本研究旨在确定在不同的电刺激肌肉收缩时间与休息时间比例下，肌肉酸痛的程度和血清肌酸激酶（CK）产生量是否存在差异。15 名受试者被随机分配到三组中的一组，每组分别接受 10 秒、15 秒的股四头肌等长电刺激，收缩间隔休息时间分别为 10 秒、30 秒和 50 秒。收缩强度维持在个体最大自主等长收缩（MVC）的 30%。在单次治疗后 24、48 和 72 小时，采集用于血清 CK 活性（肌肉损伤的指标）和感知酸痛的血液样本。所有组的血清 CK 和感知酸痛评分均显著增加。运动后血清 CK 增加在 10 秒休息期组与 30 秒和 50 秒休息期组之间存在显著差异。临床上，肌肉酸痛可能是由于初始尝试使用足以产生相当于 MVC 的 30%收缩幅度的神经肌肉电刺激（NMES）引起的。NMES 的收缩时间与休息时间比例可能会影响产生的肌肉损伤程度。《美国矫形运动物理治疗杂志》1991 年 13（6）：310-315。
