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胃肠道视频胶囊的磁性机器人操控:初步体模测试

Magnetic robotic manoeuvring of gastrointestinal video capsules: preliminary phantom tests.

作者信息

Carpi Federico, Pappone Carlo

机构信息

Interdepartmental Research Centre E. Piaggio, University of Pisa, Faculty of Engineering, via Diotisalvi, 2 Pisa, Italy.

出版信息

Biomed Pharmacother. 2008 Oct;62(8):546-9. doi: 10.1016/j.biopha.2008.07.057. Epub 2008 Aug 6.

Abstract

Ingestible video capsules enable today non-invasive and comfortable gastrointestinal explorations. As such, capsule endoscopy is progressively emerging as an attractively simple wireless technology for optical investigations of the digestive tube and, in particular, as a useful complementary diagnostic tool with respect to traditional probe endoscopy. In spite of this, capsule endoscopes still show at present a major technical lack, capable of seriously limiting their clinical efficacy: their motion cannot be controlled by an external operator. In fact, the lack of a navigation control system makes their movements and orientations totally random, being exclusively driven by visceral peristalsis and gravity. In order to provide motion control properties, a technique based on the application of external magnetic fields, capable of manoeuvring a capsule previously equipped with a magnetic component, was recently proposed. This paper presents preliminary results of the first experimental implementation of this concept with a magnetic robotic system recently introduced in the clinical practice, although for different applications in the field of cardiology. The potentialities offered by this robotic system for magnetic controls of gastrointestinal capsules were preliminarily assessed in this work with manoeuvring tests of a video capsule inside a plastic replica of a human bust. Results showed the possibility of magnetically guiding the navigation of an endoscopic capsule within the considered experimental set-up, by advantageously using the reliable robotic navigation system already employed for clinical applications. Such an outcome encourages further investigations within more challenging experimental conditions.

摘要

可摄入式视频胶囊使如今的胃肠道检查变得无创且舒适。因此,胶囊内镜正逐渐成为一种极具吸引力的简单无线技术,用于消化道的光学检查,尤其是作为传统探头内镜的一种有用的补充诊断工具。尽管如此,目前胶囊内镜仍存在一个重大技术缺陷,严重限制了其临床疗效:其运动无法由外部操作员控制。事实上,缺乏导航控制系统使得它们的运动和方向完全随机,完全由内脏蠕动和重力驱动。为了提供运动控制特性,最近提出了一种基于施加外部磁场的技术,该技术能够操纵预先配备磁性部件的胶囊。本文展示了这一概念首次实验实施的初步结果,该实验使用了最近引入临床实践的磁性机器人系统,尽管是用于心脏病学领域的不同应用。在这项工作中,通过在人体胸部塑料模型内对视频胶囊进行操纵测试,初步评估了该机器人系统对胃肠道胶囊进行磁性控制的潜力。结果表明,利用已用于临床应用的可靠机器人导航系统,有可能在考虑的实验装置内对内镜胶囊进行磁性导航引导。这一结果鼓励在更具挑战性的实验条件下进行进一步研究。

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