Pitsis Antonis A, Visouli Aikaterini N
Cardiac Surgery Department, St Luke's Hospital, Thessaloniki Heart Institute, Thessaloniki, Greece.
Curr Opin Crit Care. 2008 Oct;14(5):569-78. doi: 10.1097/MCC.0b013e3283097653.
Mechanical circulatory support has a progressively increasing impact in the treatment of heart failure. The results of mechanical circulatory support are limited not only by the severity of the disease, which necessitated initiation of support, but also by the serious device-related adverse events. Optimized patient selection, improved patient management, and advanced device technology are interdependent key factors that contributed to the recently improved outcomes. The aim of this article is to summarize the current experience in application of mechanical circulatory support, focusing on the ICU management.
Management should aim to prevent rather than treat serious complications and adverse events. Timing of intervention, optimization of the preimplantation patient status, patient and device management to ensure optimal hemodynamics, infection prevention, nutritional support, careful anticoagulation, and vigilance for early recognition and prompt treatment of 'minor' events before progression into major complications are essential elements of successful treatment.
Critical patient care is a valuable adjunct to successful application of mechanical circulatory support, but it cannot counterbalance a late intervention, neither can it be fruitful in treating irreversible organ damage. Current management includes careful application of treatment protocols adjusted to recent experience, and also individualized care by a specialized team.
机械循环支持在心力衰竭治疗中的影响日益增大。机械循环支持的结果不仅受疾病严重程度(这使得必须启动支持治疗)的限制,还受与设备相关的严重不良事件的限制。优化患者选择、改善患者管理以及先进的设备技术是相互依存的关键因素,这些因素促成了近期治疗结果的改善。本文旨在总结机械循环支持应用的当前经验,重点关注重症监护病房(ICU)管理。
管理应旨在预防而非治疗严重并发症和不良事件。干预时机、植入前患者状态的优化、患者和设备管理以确保最佳血流动力学、感染预防、营养支持、谨慎抗凝以及警惕在“轻微”事件进展为主要并发症之前进行早期识别和及时治疗,这些都是成功治疗的关键要素。
重症患者护理是机械循环支持成功应用的重要辅助手段,但它无法弥补延迟干预,也无法有效治疗不可逆的器官损伤。当前的管理包括根据近期经验谨慎应用调整后的治疗方案,以及由专业团队提供个性化护理。