Uchikov A, Nonchev B, Danev V, Murdzhev K, Vladeva S, Terzieva D
Khirurgiia (Sofiia). 2006(3):9-11.
The aim of this study was to evaluate the results of the surgical treatment of patients with thyrotoxicosis in three surgical clinics in Plovdiv. PATIENTS AND MEDHOTS: We studied 90 patients, who underwent surgical treatment for thyrotoxicosis between 2000-2004. Of those 19 men (21%) and 71 women (79%); men:women = 1:3.74; mean age 38 +/- 8.3 years. The nosological distribution was as follows: Graves' disease--72 subjects (80.00%), solitary toxic adenoma--4 subjects (4.40%), toxic nodular goiter--14 subjects (15.60%). 77 subtotal thyroidectomies (85%) and 9 total thyroidectomies were performed. Patients with solitary toxic adenoma underwent lobectomy.
Massive bleeding witch required revision and haemostasis was encountered in 1 patient. Transient laryngeal nerve injury occurred in 3 patients (3.33%), and temporary hypoparathyroidism in 6 subjects (6.67%), necessitating calcium supplementation. One year postoperatively, 49.35% (n = 38) of the patients who have undergone subtotal thyroidectomy were euthyroid, 45.45% (n = 35) developed hypothyroidism, and 5.2% (n = 4) relapsed.
Our results indicate that surgery is safe and effective for patients with thyrotoxicosis referred for radical treatment. Because of the high rate of postoperative thyroid disfunction, assessment of the non-operative factors, witch influence the functional results, is recommended.
本研究旨在评估普罗夫迪夫三家外科诊所对甲状腺毒症患者进行手术治疗的结果。
我们研究了2000年至2004年间接受甲状腺毒症手术治疗的90例患者。其中男性19例(21%),女性71例(79%);男女比例为1:3.74;平均年龄38±8.3岁。疾病分类分布如下:格雷夫斯病——72例(80.00%),孤立性毒性腺瘤——4例(4.40%),毒性结节性甲状腺肿——14例(15.60%)。实施了77例次甲状腺次全切除术(85%)和9例次甲状腺全切除术。孤立性毒性腺瘤患者接受了叶切除术。
1例患者发生大量出血,需要再次手术和止血。3例患者(3.33%)出现暂时性喉返神经损伤,6例患者(6.67%)出现暂时性甲状旁腺功能减退,需要补充钙剂。甲状腺次全切除术后1年,49.35%(n = 38)的患者甲状腺功能正常,45.45%(n = 35)发生甲状腺功能减退,5.2%(n = 4)复发。
我们的结果表明,手术对于接受根治性治疗的甲状腺毒症患者是安全有效的。由于术后甲状腺功能障碍发生率较高,建议评估影响功能结果的非手术因素。