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[复发性甲状腺肿:我们的经验]

[Recurrent goitre: our experience].

作者信息

Calò Pietro Giorgio, Tuveri Massimiliano, Pisano Giuseppe, Tatti Alberto, Medas Fabio, Donati Marcello, Nicolosi Angelo

机构信息

Dipartimento di Chirurgia e Scienze Odontostomatologiche, Università degli Studi di Cagliari

出版信息

Chir Ital. 2009 Sep-Dec;61(5-6):545-9.

PMID:20380256
Abstract

Recurrence after conservative thyroid surgery ranges from 7 to 40%. Risk factors for recurrence are female sex, multiple nodules in the resected lobe and lack of postoperative LT4 therapy. Indications for reoperation are suspected malignancy, recurrent thyrotoxicosis and recurrent uninodular or multinodulare goitre. From 2002 to 2008, 2149 total thyroidectomies were performed. Ninety-two patients had a completion thyroidectomy. The indication was recurrent multinodular goitre in 81, recurrent thyrotoxicosis in 3, and suspected malignancy in 8. Bilateral completion thyroidectomy was performed in 63 cases, lobectomy in 27 cases, removal of a mediastinal recurrence in 1 case and removal of a pyramidal remnant in 1 case. Histological examination revealed papillary cancer in 18 patients and follicular cancer in 1. Mean operative time was 140 minutes (range: 60-260). All patients were submitted to a minimum follow-up of 6 months. Temporary hypoparathyroidism occurred in 36 patients (39.1%) and definitive hypoparathyroidism in 7 patients (7.6%). Transient recurrent laryngeal nerve palsy occurred in 3 cases (3.2%) and permanent nerve palsy in 1 (1.1%). In 3 cases (3.2%) surgical revision of haemostasis was necessary for postoperative haemorrhage. Total thyroidectomy is the treatment of choice in multinodular goitre. In the cases in which reoperation is necessary, the intervention must be performed by an experienced surgeon.

摘要

甲状腺保守性手术后的复发率在7%至40%之间。复发的危险因素包括女性、切除叶内存在多个结节以及术后未进行左甲状腺素(LT4)治疗。再次手术的指征为疑似恶性肿瘤、复发性甲状腺毒症以及复发性单结节或多结节性甲状腺肿。2002年至2008年期间,共进行了2149例全甲状腺切除术。92例患者接受了甲状腺全切术。其中81例的指征为复发性多结节性甲状腺肿,3例为复发性甲状腺毒症,8例为疑似恶性肿瘤。63例行双侧甲状腺全切术,27例行叶切除术,1例行纵隔复发灶切除术,1例行锥体叶残留切除术。组织学检查发现18例为乳头状癌,1例为滤泡状癌。平均手术时间为140分钟(范围:60 - 260分钟)。所有患者至少接受了6个月的随访。36例患者(39.1%)发生了暂时性甲状旁腺功能减退,7例患者(7.6%)发生了永久性甲状旁腺功能减退。3例患者(3.2%)出现了暂时性喉返神经麻痹,1例患者(1.1%)出现了永久性神经麻痹。3例患者(3.2%)因术后出血需要进行止血手术修正。全甲状腺切除术是多结节性甲状腺肿的首选治疗方法。在需要再次手术的病例中,干预必须由经验丰富的外科医生进行。

相似文献

1
[Recurrent goitre: our experience].[复发性甲状腺肿:我们的经验]
Chir Ital. 2009 Sep-Dec;61(5-6):545-9.
2
Risk factors in reoperative thyroid surgery for recurrent goitre: our experience.复发性甲状腺肿再次手术的危险因素:我们的经验
G Chir. 2012 Oct;33(10):335-8.
3
Recurrent laryngeal nerve injury and preservation in thyroidectomy.甲状腺切除术中喉返神经损伤与保护
Saudi Med J. 2005 Nov;26(11):1746-9.
4
Reoperative surgery for thyroid disease.甲状腺疾病的再次手术
Langenbecks Arch Surg. 2007 Nov;392(6):685-91. doi: 10.1007/s00423-007-0201-6. Epub 2007 Jun 26.
5
[Complications in surgical treatment of thyroid diseases].[甲状腺疾病外科治疗中的并发症]
Otolaryngol Pol. 2006;60(2):165-70.
6
[Surgical indications and techniques in Basedow's disease, multinodular goiter and thyroid cancers].[格雷夫斯病、结节性甲状腺肿和甲状腺癌的手术指征及技术]
Rev Med Suisse Romande. 2001 May;121(5):337-9.
7
[Is primary total thyroidectomy justified in benign multinodular goiter? Results of a prospective quality assurance study of 45 hospitals offering different levels of care].[原发性甲状腺全切除术用于良性结节性甲状腺肿是否合理?对45家提供不同护理水平医院的前瞻性质量保证研究结果]
Chirurg. 2003 May;74(5):437-43. doi: 10.1007/s00104-002-0605-3.
8
Total compared with subtotal thyroidectomy in benign nodular disease: personal series and review of published reports.良性结节性疾病中行甲状腺全切除术与次全切除术的比较:个人病例系列及已发表报告综述
Eur J Surg. 1998 Jul;164(7):501-6. doi: 10.1080/110241598750005840.
9
[Reoperations of the thyroid gland].[甲状腺再次手术]
Chirurgia (Bucur). 2007 May-Jun;102(3):297-302.
10
Analysis and prevention of recurrent goiter.复发性甲状腺肿的分析与预防
Surg Gynecol Obstet. 1993 Apr;176(4):319-22.

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Langenbecks Arch Surg. 2015 Feb;400(2):253-8. doi: 10.1007/s00423-014-1258-7. Epub 2014 Nov 29.
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Identification alone versus intraoperative neuromonitoring of the recurrent laryngeal nerve during thyroid surgery: experience of 2034 consecutive patients.甲状腺手术中喉返神经的单独识别与术中神经监测:2034 例连续患者的经验。
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Complications in thyroid resurgery: a single institutional experience on 233 patients from a whole series of 4,752 homogeneously treated patients.甲状腺再次手术的并发症:来自4752例接受同质化治疗患者的整个队列中233例患者的单机构经验。
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