Ausayakhun Sakarin, Itthipunkul Nimitr, Patikulsila Direk, Choovuthayakorn Janejit, Kunavisarut Paradee, Wattananikorn Sopa, Ausayakhun Somsanguan
Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
J Med Assoc Thai. 2008 Aug;91(8):1239-43.
Endophthalmitis is one of the most serious complications of ophthalmic surgery, which includes postoperative cataract extraction. Outbreak of acute postoperative endophthalmitis after cataract surgery has been reported in Thailand and other countries.
To describe an outbreak of acute postoperative endophthalmitis after cataract surgery that was referred to Chiang Mai University Hospital during March 2006.
Observational case series were made from the records of inpatients and outpatients, who had been referred for treatment of acute postoperative endophthalmitis after cataract surgery at a district hospital in northern Thailand. The surgery was conducted on two consecutive days by volunteer ophthalmologists of a non-profit foundation from Bangkok.
In this outbreak, the authors recorded 31 endophthalmitis cases, with 33 eyes (bilateral 2 cases). Of the 33 endophthalmitis eyes, 32 occurred following extracapsular cataract extraction with intraocular lens and one after the secondary intraocular lens implant. Microbiological investigations in the hospital were done with aqueous tapping, vitreous tapping, and vitreous from pars plana vitrectomy. Gram-positive cocci were detected from vitreous tapping in four eyes. Thirty-two cases were managed with intravitreous antibiotics, one with subconjunctival antibiotic only, and all eyes were treated with fortified topical antibiotics. Fifteen eyes underwent pars plana vitrectomy Assessment of visual acuity (VA) before and after treatment showed improvement in 75.8% (25/33), decrease of VA in 9.1% (3/33), while visual acuity remained stable in 15.2% (5/33).
In high-volume cataract surgery, an outbreak of endophthalmitis is always possible. Prompt and appropriate treatment can improve the visual outcome.
眼内炎是眼科手术(包括白内障摘除术后)最严重的并发症之一。泰国及其他国家均有白内障手术后急性术后眼内炎爆发的报道。
描述2006年3月转诊至清迈大学医院的白内障手术后急性术后眼内炎爆发情况。
对泰国北部一家地区医院收治的因白内障手术后急性术后眼内炎前来治疗的住院和门诊患者记录进行观察性病例系列研究。手术由来自曼谷的一个非营利基金会的志愿眼科医生连续两天进行。
在此次爆发中,作者记录了31例眼内炎病例,涉及33只眼(2例为双眼)。在这33只眼内炎眼中,32例发生于白内障囊外摘除联合人工晶状体植入术后,1例发生于二期人工晶状体植入术后。医院通过房水穿刺、玻璃体穿刺以及经睫状体平坦部玻璃体切割术获取的玻璃体进行微生物学检查。4只眼的玻璃体穿刺液中检测到革兰氏阳性球菌。32例采用玻璃体腔内注射抗生素治疗,1例仅采用结膜下注射抗生素治疗,所有眼睛均接受强化局部抗生素治疗。15只眼接受了经睫状体平坦部玻璃体切割术。治疗前后视力评估显示,75.8%(25/33)的患者视力改善,9.1%(3/33)的患者视力下降,15.2%(5/33)的患者视力保持稳定。
在大量白内障手术中,眼内炎爆发始终有可能发生。及时且恰当的治疗可改善视力预后。