Khosla Rohit K, Mabry Kelly, Castiglione Charles L
University of Washington, Seattle, Washington, USA.
Cleft Palate Craniofac J. 2008 Sep;45(5):501-10. doi: 10.1597/07-063.1. Epub 2008 Jan 3.
To review the clinical outcomes following the Furlow Z-plasty for primary cleft palate repair. The primary objective was to determine if the presence of an associated sequence or syndrome (i.e., Pierre Robin sequence), age at palate repair, cleft type, or surgeon experience influenced speech outcomes after a Furlow Z-plasty.
The outcomes of 140 patients who underwent palate repair were analyzed retrospectively. Speech evaluations were performed to score the severity of hypernasality, nasal escape, articulation errors, and velopharyngeal insufficiency.
The mean age at latest evaluation was 4 years 9 months (age range 2 years old to 12 years old and 4 months). Of the 140 patients, 83% had no evidence of hypernasality, 91% had no presence of nasal escape, and 69% had no articulation errors. Overall, 84% of patients had no evidence of velopharyngeal insufficiency. Secondary posterior pharyngeal flap to correct velopharyngeal insufficiency was required in only 2.1% of patients. The formation of an oronasal fistula occurred in only 3.6% of patients. Nonsyndromic patients with Pierre Robin sequence and syndromic patients did just as well as purely nonsyndromic patients in terms of velopharyngeal insufficiency, hypernasality, and nasal escape. Syndromic patients were more likely to make mild-to-moderate articulation errors. In addition, age at palate repair, cleft type, and surgeon experience had no statistically significant effect on speech results.
The Furlow Z-plasty yielded excellent speech results in our patient population with minimal and acceptable rates of fistula formation, velopharyngeal insufficiency, and the need for additional corrective surgery.
回顾Furlow Z成形术用于一期腭裂修复后的临床疗效。主要目的是确定是否存在相关序列征或综合征(即Pierre Robin序列征)、腭裂修复时的年龄、腭裂类型或外科医生经验对Furlow Z成形术后的语音效果产生影响。
对140例行腭裂修复术患者的疗效进行回顾性分析。进行语音评估以对高鼻音、鼻漏气、发音错误和腭咽闭合不全的严重程度进行评分。
最近一次评估时的平均年龄为4岁9个月(年龄范围为2岁至12岁4个月)。140例患者中,83%无高鼻音表现,91%无鼻漏气,69%无发音错误。总体而言,84%的患者无腭咽闭合不全表现。仅2.1%的患者需要二期咽后瓣修复腭咽闭合不全。仅3.6%的患者发生口鼻瘘。在腭咽闭合不全、高鼻音和鼻漏气方面,伴有Pierre Robin序列征的非综合征患者和综合征患者与单纯非综合征患者表现相当。综合征患者更易出现轻至中度发音错误。此外,腭裂修复时的年龄、腭裂类型和外科医生经验对语音结果无统计学显著影响。
在我们的患者群体中,Furlow Z成形术取得了优异的语音效果,瘘管形成、腭咽闭合不全及需要额外矫正手术的发生率低且可接受。