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瑞典儿童和年轻人通过不同食品接触二噁英类污染物的情况。

Exposure to dioxin-like pollutants via different food commodities in Swedish children and young adults.

作者信息

Bergkvist Charlotte, Oberg Mattias, Appelgren Malin, Becker Wulf, Aune Marie, Ankarberg Emma Halldin, Berglund Marika, Håkansson Helen

机构信息

Institute of Environmental Medicine, Karolinska Institutet, P.O. Box 210, SE-171 77, Stockholm, Sweden.

出版信息

Food Chem Toxicol. 2008 Nov;46(11):3360-7. doi: 10.1016/j.fct.2008.07.029. Epub 2008 Aug 26.

Abstract

The dietary intake of polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and biphenyls (PCBs) in terms of toxic equivalents (TEQs) was investigated in Swedish children and young adults. Exposure was estimated from concentration data of six groups of individual food commodities (meat, fish, dairy products, egg, edible fats and other foodstuff) combined with food intake data from a 7-day record book obtained from 670 individuals aged 1-24 years. The results showed that Swedish boys and girls, up to the age of ten, had a median TEQ intake that exceeded the tolerable daily intake (TDI) of 2 pg TEQ/kg body weight. Children exceeding the TDI varied from almost all individuals among the youngest children to about 20% among young men and women. Dairy and fish products were the main sources of exposure for the average child, accounting for 59% of the total TEQ intake. The individuals most highly exposed were, on the other hand, characterized by a high consumption of fish. Since children constitute a vulnerable group, results obtained from the present study show that it is essential to perform age specific dietary intake assessments of pollutants and more carefully consider sensitive and/or highly exposed groups in the population in the risk management processes.

摘要

对瑞典儿童和年轻人膳食中多氯二苯并对二恶英(PCDDs)、二苯并呋喃(PCDFs)和多氯联苯(PCBs)的毒性当量(TEQs)摄入量进行了调查。根据六类单一食品(肉类、鱼类、乳制品、蛋类、食用脂肪和其他食品)的浓度数据,结合从670名1至24岁个体的7天饮食记录簿中获取的食物摄入量数据,估算暴露量。结果显示,瑞典10岁及以下的男孩和女孩,其毒性当量摄入量中位数超过了每日耐受摄入量(TDI)——2皮克毒性当量/千克体重。超过每日耐受摄入量的儿童比例,从最小年龄段的几乎所有个体,到青年男女中的约20%不等。对于普通儿童而言,乳制品和鱼类产品是主要的暴露源,占总毒性当量摄入量的59%。另一方面,暴露程度最高的个体,其特点是鱼类消费量高。由于儿童是弱势群体,本研究结果表明,在风险管理过程中,对污染物进行特定年龄的膳食摄入量评估,并更仔细地考虑人群中的敏感和/或高暴露群体至关重要。

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