Sasamoto Takeo, Ushio Fusao, Kikutani Norihisa, Saitoh Yuki, Yamaki Yumiko, Hashimoto Tsuneo, Horii Shozo, Nakagawa Jun-ichi, Ibe Akihiro
Division of Food Contaminants, Tokyo Metropolitan Institute of Public Health, Tokyo 169-0073, Japan.
Chemosphere. 2006 Jul;64(4):634-41. doi: 10.1016/j.chemosphere.2005.10.057. Epub 2005 Dec 27.
A study of the dietary intake of dioxins, consisting of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (dioxin-like PCBs) through foods retailed in the metropolitan Tokyo area from 1999 to 2004 was carried out by the total diet-market basket method on the basis of food classification (14 groups) and the data on food consumption in the Tokyo region obtained from the Japan Nutrition Survey. The daily intake of dioxins per kg of body weight for a 50 kg average adult body was 2.18 pg TEQ/kg/day in 1999, 1.87 pg TEQ/kg/day in 2000, 1.25 pg TEQ/kg/day in 2001, 1.60 pg TEQ/kg/day in 2002 and 2003 and 1.55 pg TEQ/kg/day in 2004, respectively. These amounts were less than the tolerable daily intake (TDI) of 4 pg TEQ/kg/day for dioxins established in Japan. The dioxins taken daily through fish and shellfish (group 10) accounted for more than 50% of sum WHO-TEQs. In addition, more than 90% of the daily intake of dioxins was taken through fish and shellfish (group 10), meat and eggs (group 11), milk and dairy products (group 12). Also, this study clearly showed that the ratio of dioxin-like PCBs in the daily intake of dioxins was increasing yearly because the reduction rate of dioxin-like PCBs was lower than that of PCDDs and PCDFs in foods.
采用总膳食—市场篮子法，基于食物分类（14组）以及从日本营养调查获得的东京地区食物消费数据，对1999年至2004年东京都市区零售食品中由多氯代二苯并 - 对 - 二恶英（PCDDs）、多氯代二苯并呋喃（PCDFs）和类二恶英多氯联苯（类二恶英PCBs）组成的二恶英膳食摄入量进行了研究。平均体重50千克的成年人每千克体重每日二恶英摄入量在1999年为2.18皮克毒性当量/千克/天，2000年为1.87皮克毒性当量/千克/天，2001年为1.25皮克毒性当量/千克/天，2002年和2003年为1.60皮克毒性当量/千克/天，2004年为1.55皮克毒性当量/千克/天。这些数值均低于日本规定的二恶英每日耐受摄入量（TDI）4皮克毒性当量/千克/天。通过鱼类和贝类（第10组）每日摄入的二恶英占世界卫生组织毒性当量总和的50%以上。此外，每日二恶英摄入量的90%以上通过鱼类和贝类（第10组）、肉类和蛋类（第11组）、牛奶及奶制品（第12组）摄入。而且，该研究清楚地表明，由于食品中类二恶英PCBs的减少率低于PCDDs和PCDFs，二恶英每日摄入量中类二恶英PCBs的比例逐年增加。
