Wizel Benjamin, Nyström-Asklin Johanna, Cortes Claudio, Tvinnereim Amy
Department of Microbiology and Immunology, University of Texas Health Science Center, Tyler, TX 75708, USA.
Microbes Infect. 2008 Nov-Dec;10(14-15):1420-30. doi: 10.1016/j.micinf.2008.08.006. Epub 2008 Aug 26.
Chlamydia infections constitute a major public health problem. Although multiple arms of the immune system participate in the control of Chlamydia in infected hosts, T lymphocytes are essential. This review focuses on the roles that CD8(+)T cells may play in immunoprotection and immunopathology following recognition of Chlamydia-infected cells.
衣原体感染是一个重大的公共卫生问题。尽管免疫系统的多个分支参与了对受感染宿主中衣原体的控制,但T淋巴细胞至关重要。本综述重点关注CD8(+)T细胞在识别衣原体感染细胞后在免疫保护和免疫病理中可能发挥的作用。