Naval Neeraj S, Nyquist Paul A, Carhuapoma J Ricardo
Department of Neurology, Division of Neurosciences Critical Care, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
Neurosurg Clin N Am. 2008 Jul;19(3):415-23, v. doi: 10.1016/j.nec.2008.07.014.
Spontaneous intracerebral hemorrhage (ICH) has the highest mortality of all cerebrovascular events. Thirty-day mortality approaches 50%, and only 20% of survivors achieve meaningful functional recovery at 6 months. Many clinicians believe that effective therapies are lacking; however, this is changing because of new data on the pathophysiology and treatment of ICH, particularly research establishing the role of medical therapies to promote hematoma stabilization. This article provides updates to a recent publication discussing basic principles of ICH management, including initial stabilization, the prevention of hematoma growth, treatment of complications, and identification of the underlying etiology. Minimally invasive surgery (MIS) to reduce clot size is also discussed, with the goal of preserving neurologic function through reduction in parenchymal damage from edema formation.
