Kaufman L D, Heinicke M H, Hamburger M, Gorevic P D
Department of Medicine, State University of New York, Stony Brook 11794-8161.
Clin Exp Rheumatol. 1991 May-Jun;9(3):265-9.
Serological studies conducted on sera from a group of 31 male SLE patients revealed a 32% prevalence of 7S IgM and a 9.7% prevalence of IgA deficiency. Previous reports using similar methods indicated a higher (43-50%) prevalence of 7S IgM than was found in studies involving predominantly females with SLE (15-18%), and an overall prevalence of IgA deficiency ranging from 0.95% to 4.6%. Males resembled females in the prevalence of Fc-receptor specific reticuloendothelial system dysfunction, correlating with levels of circulating immune complex-like material and disease activity.
对一组31名男性系统性红斑狼疮(SLE)患者的血清进行的血清学研究显示,7S IgM的患病率为32%,IgA缺乏症的患病率为9.7%。以前使用类似方法的报告表明,7S IgM的患病率(43%-50%)高于主要涉及女性SLE患者的研究中发现的患病率(15%-18%),IgA缺乏症的总体患病率在0.95%至4.6%之间。在Fc受体特异性网状内皮系统功能障碍的患病率方面,男性与女性相似,这与循环免疫复合物样物质的水平和疾病活动相关。