Weng Z G, Lin Z L, Zhang H S, Sheng M L, Ma J Y, Wu C F
Institute of Radiation Medicine, Shanghai Medical University.
Chin Med J (Engl). 1991 Jul;104(7):581-4.
105 patients with late stage radiation skin injury were treated from 1970 to 1986, using drugs combined with surgical intervention according to the clinical features of the injury. Drug therapy consisted of topical application of urea, antibiotics, trypsin and elastase, and systematic use of alpha 2-Macroglobulin. Of 62 patients receiving medication, 55 (88.7%) were completely or basically treated and 7 failed. Of 51 lesions of 43 patients receiving surgical treatment, 47 healed by first intention. In 4 patients, necrosis of partial and/or peripheral skin flaps healed after renewed repair.
1970年至1986年期间，对105例晚期放射性皮肤损伤患者进行了治疗，根据损伤的临床特征采用药物与手术干预相结合的方法。药物治疗包括局部应用尿素、抗生素、胰蛋白酶和弹性蛋白酶，以及全身应用α2-巨球蛋白。在62例接受药物治疗的患者中，55例（88.7%）得到完全或基本治愈，7例治疗失败。在接受手术治疗的43例患者的51处损伤中，47处一期愈合。4例患者部分和/或周边皮瓣坏死经再次修复后愈合。
