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特纳综合征患者单卵裂期胚胎选择性移植后卵母细胞捐赠的不良结局。

Poor outcome in oocyte donation after elective transfer of a single cleavage-stage embryo in Turner syndrome patients.

作者信息

Bodri Daniel, Guillén Juan José, Schwenn Katja, Casadesus Sara, Vidal Ricard, Coll Oriol

机构信息

Clínica EUGIN, Barcelona, Spain.

出版信息

Fertil Steril. 2009 Apr;91(4 Suppl):1489-92. doi: 10.1016/j.fertnstert.2008.07.1762. Epub 2008 Sep 14.

Abstract

In this retrospective, matched study we evaluated the outcome of 31 oocyte donation (OD) cycles performed in 29 Turner syndrome (TS) patients involving the elective transfer of a single, fresh cleavage-stage (day 2 to 3) embryo. Due to the fact that ongoing pregnancy rate was statistically significantly lower (3.2% versus 22.5%) in TS patients when compared with matched, non-TS recipients, other strategies (such as single blastocyst transfer) should be evaluated that could enable better outcomes and at the same time avoid potential complications related to multiple pregnancies in this particularly high obstetric-risk group.

摘要

在这项回顾性配对研究中,我们评估了29例特纳综合征(TS)患者进行的31个卵母细胞捐赠(OD)周期的结果,这些周期涉及选择性移植单个新鲜卵裂期(第2至3天)胚胎。由于与配对的非TS受体相比,TS患者的持续妊娠率在统计学上显著较低(3.2%对22.5%),因此应评估其他策略(如单囊胚移植),这些策略可以实现更好的结果,同时避免在这个产科风险特别高的群体中与多胎妊娠相关的潜在并发症。

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