Saghiri Mohammad Ali, Lotfi Mehrdad, Saghiri Ali Mohammad, Vosoughhosseini Sepideh, Fatemi Ali, Shiezadeh Vahab, Ranjkesh Bahram
Department of Biomedical Engineering, Islamic Azad University, Tehran, Iran.
J Endod. 2008 Oct;34(10):1226-9. doi: 10.1016/j.joen.2008.07.017. Epub 2008 Aug 23.
The aim of the present study was to evaluate microleakage of mineral trioxide aggregate (MTA) used as a root-end filling material after its exposure to a range of acidic environments during hydration. Seventy single-rooted teeth were divided into 4 experimental and 2 control groups. All the teeth were instrumented, and their apices were resected. Root-end cavities were filled with white MTA in the experimental groups. In the control groups root-end cavities were not filled. Root-end fillings were exposed to acidic environments with pH values of 4.4, 5.4, 6.4, or 7.4 for 3 days in the experimental groups. Microleakage was evaluated by using bovine serum albumin. The evaluation was conducted at 24-hour intervals for 80 days. Data were analyzed by using one-way analysis of variance and a post hoc Tukey test. The earliest bovine serum albumin microleakage was observed in a pH value of 4.4 followed by pH values of 5.4, 6.4, and 7.4, respectively. There was a significantly longer time necessary for leakage to occur in samples stored in higher pH values (P < .000).
本研究的目的是评估矿物三氧化物凝聚体（MTA）作为根尖充填材料在水化过程中暴露于一系列酸性环境后其微渗漏情况。70颗单根牙被分为4个试验组和2个对照组。所有牙齿均进行根管预备，并切除根尖。试验组根尖窝洞用白色MTA充填。对照组根尖窝洞不充填。试验组将根尖充填物暴露于pH值为4.4、5.4、6.4或7.4的酸性环境中3天。使用牛血清白蛋白评估微渗漏情况。在80天内每隔24小时进行一次评估。采用单因素方差分析和事后Tukey检验对数据进行分析。最早观察到牛血清白蛋白微渗漏的是pH值为4.4的组，其次分别是pH值为5.4、6.4和7.4的组。储存在较高pH值环境中的样本发生渗漏所需时间明显更长（P <.000）。
