使用三维电阻抗断层成像技术的乳腺成像

Breast imaging using 3D electrical impedence tomography.

作者信息

Prasad Sachin N, Houserkova Dana, Campbell Jan

机构信息

Department of Radiology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

出版信息

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2008 Jun;152(1):151-4. doi: 10.5507/bp.2008.024.

DOI:10.5507/bp.2008.024

PMID:18795091

Abstract

AIM

To determine the diagnostic efficiency of 3D Eletrical Impedance Tomography (EIT) compared to Mammography (MG) and Ultrasonography (USG) in imaging the breast.

MATERIALS AND METHODS

A group of 88 patients presenting with various breast complaints was examined using combined Mammography and Ultrasonography (MG & USG) or either of these modalities alone. The same patients were then examined using the 3D EIT imaging system "MEIK". The findings were then compared. The sensitivity of these modalities for this group of patients were later determined and statistically analysed.

RESULTS

Of the total of 88 patients, 59 findings were "suspicious" by any of the 3 modalities alone or by their combination. EIT had a sensitivity of 77.8 % compared to MG with a sensitivity of 83.3 % and USG with a sensitivity of 94.4 % regarding cases of fibrocystic mastitis. For cases involving cysts, EIT had 100 % sensitivity which was the same as that for USG compared to MG with a sensitivity of only 81 %. Among cases of fibroadenoma, EIT had a sensitivity of just 68.8 % compared to MG with a sensitivity of 87.5 % and USG with a sensitivity of 75 %. Finally among cases of carcinoma, EIT had a sensitivity of 75 % compared to the sensitivity of 100 % of MG and USG in our group of patients. The study revealed that there was no overall significant difference in sensitivity between MG-USG (p = 0.219) and MG-EIT (p = 0.779) and USG-EIT (p = 0.169). However, in regard to identifying cysts there was significant difference in the sensitivity of MG compared to USG & EIT suggesting that EIT has a role in these cases.

CONCLUSION

Electrical impedance could be used as an adjunct to Mammography and Ultrasonography for breast cancer detection. However, the differentiation of malignant from benign lesions based on impedance measurements needs further investigation. Multifrequency electrical impedance imaging appears the most promising for detecting breast malignancies but methodological improvements need to be made to realise its potential.

摘要

目的

确定与乳腺X线摄影（MG）和超声检查（USG）相比，三维电阻抗断层成像（EIT）在乳腺成像中的诊断效率。

材料与方法

对一组88例有各种乳腺问题的患者进行联合乳腺X线摄影和超声检查（MG & USG）或单独使用其中一种检查方法。然后使用三维EIT成像系统“MEIK”对同一组患者进行检查。随后对检查结果进行比较。之后确定并统计分析这些检查方法对该组患者的敏感性。

结果

在总共88例患者中，单独使用或联合使用这三种检查方法中的任何一种发现了59个“可疑”结果。对于纤维囊性乳腺炎病例，EIT的敏感性为77.8%，MG的敏感性为83.3%，USG的敏感性为94.4%。对于囊肿病例，EIT的敏感性为100%，与USG相同，而MG的敏感性仅为81%。在纤维腺瘤病例中，EIT的敏感性仅为68.8%，MG的敏感性为87.5%，USG的敏感性为75%。最后在癌病例中，EIT的敏感性为75%，而在我们的患者组中MG和USG的敏感性为100%。研究表明，MG-USG（p = 0.219）、MG-EIT（p = 0.779）和USG-EIT（p = 0.169）之间在敏感性上没有总体显著差异。然而，在识别囊肿方面，MG与USG和EIT的敏感性存在显著差异，这表明EIT在这些病例中具有作用。