Vokurka Jiri, Olejnik Juraj, Jedlicka Vaclav, Vesely Martin, Ciernik Jan, Paseka Tomas
lst Department of Surgery, Masaryk University, St. Anne's Hospital, Pekarska 53, 656 91 Brno, Czech Republic.
Hepatogastroenterology. 2008 Jul-Aug;55(85):1349-52.
BACKGROUND/AIMS: Acute mesenteric ischemia (AMI) is a serious disease in old age with low incidence but with a very high mortality rate (60-70%). The etiology is either primary (embolism or thrombosis of mesenteric arteries or veins, non-occlusive mesenteric ischemia) or secondary (mechanical obstruction such as intestinal volvulus, intussusception, tumor-caused compression). Independent of the origin of the illness, the clinical-pathological picture is the same: intestinal ischemia with subsequent necrosis. The aim of this study was to ascertain which underlying conditions lead to increased probability of development of acute mesenteric ischemia.
Two hundred and fifteen patients with a primary form of AMI were treated in the years 1991-2007, in the 1st Clinic of Surgery in Brno, Czech Republic and in the Department of General Surgery, Derer's University Hospital in Bratislava, Slovak Republic; the results of the treatment have been statistically evaluated.
The probability of arterial mesenteric ischemia development rises significantly (p < 0.05) in patients with a history of atrial fibrillation and/or myocardial infarction. This probability is also significantly higher in smokers with symptoms of hypertension and clinical signs of abdominal angina (p < 0.05).
背景/目的：急性肠系膜缺血（AMI）是一种好发于老年人的严重疾病，发病率低但死亡率极高（60 - 70%）。其病因要么是原发性的（肠系膜动脉或静脉栓塞或血栓形成、非闭塞性肠系膜缺血），要么是继发性的（机械性梗阻，如肠扭转、肠套叠、肿瘤所致压迫）。无论病因如何，临床病理表现相同：肠道缺血继而坏死。本研究的目的是确定哪些基础疾病会导致急性肠系膜缺血发生的可能性增加。
1991年至2007年期间，捷克布尔诺第一外科诊所和斯洛伐克布拉迪斯拉发德雷尔大学医院普通外科对215例原发性AMI患者进行了治疗；对治疗结果进行了统计学评估。
有房颤和/或心肌梗死病史的患者发生肠系膜动脉缺血的可能性显著升高（p < 0.05）。有高血压症状且有腹部绞痛临床体征的吸烟者发生这种情况的可能性也显著更高（p < 0.05）。
