Mas A J, Carmona L, Valverde M, Ribas B
Rheumatology Department, Hospital Son Llàtzer, Palma de Mallorca, Spain.
Clin Exp Rheumatol. 2008 Jul-Aug;26(4):519-26.
To estimate the prevalence of fibromyalgia (FM) and to compare some descriptive epidemiological and quality of life data between persons with and without FM criteria in a representative sample of the general Spanish population.
Cross sectional study of 2,192 Spaniards aged 20 or above, selected by cluster sampling. Subjects were invited to a structured interview carried out by trained rheumatologists to ascertain various musculoskeletal disorders. The visit included screening and examination, validated instruments for measuring function (HAQ) and quality of life (SF-12) and questions about socio-demographic characteristics and musculoskeletal, mental, and other general symptoms. FM was suspected in subjects with widespread pain for more than three months. FM was defined by theAmerican College of Rheumatology classification criteria. All estimates are adjusted to sampling scheme.
The prevalence of FM in Spain is 2.4% (95% CI: 1.5-3.2). FM is significantly more frequent in women (4.2%) than in men (0.2%), with an OR for women of 22.5 (95%CI: 7.2- 69.9), mainly in the 40-49 years age interval. It is more frequent in rural (4.1%) than in urban settings (1.7%), with an OR for rural settings of 2.5 (95%CI: 1.03-5.9). FM is associated with a low educational level, to a low social class, and to self-reported depression. The scores in the HAQ and in the SF-12 were significantly lower in FM subjects, despite adjustment by covariates.
FM has a high prevalence in the general population. FM is associated to female gender, comorbidities, age between 40 and 59 years, and a rural setting. Persons fulfilling FM criteria show impaired functioning and quality of life.
在西班牙普通人群的代表性样本中，估计纤维肌痛（FM）的患病率，并比较符合和不符合FM标准的人群之间的一些描述性流行病学和生活质量数据。
采用整群抽样法对2192名20岁及以上的西班牙人进行横断面研究。邀请受试者接受由训练有素的风湿病学家进行的结构化访谈，以确定各种肌肉骨骼疾病。此次访视包括筛查和检查、用于测量功能（健康评估问卷，HAQ）和生活质量（简短健康调查问卷，SF-12）的有效工具，以及关于社会人口学特征和肌肉骨骼、精神及其他一般症状的问题。对有超过三个月广泛性疼痛的受试者怀疑患有FM。FM由美国风湿病学会分类标准定义。所有估计值均根据抽样方案进行了调整。
西班牙FM的患病率为2.4%（95%置信区间：1.5 - 3.2）。FM在女性（4.2%）中比在男性（0.2%）中明显更常见，女性的优势比为22.5（95%置信区间：7.2 - 69.9），主要集中在40 - 49岁年龄区间。在农村地区（4.1%）比在城市地区（1.7%）更常见，农村地区的优势比为2.5（95%置信区间：1.03 - 5.9）。FM与低教育水平、低社会阶层以及自我报告的抑郁症有关。尽管进行了协变量调整，但FM受试者的HAQ和SF-12得分仍显著较低。
FM在普通人群中患病率较高。FM与女性性别、合并症、40至59岁年龄以及农村环境有关。符合FM标准的人群功能和生活质量受损。
