Fernandez-Lopez J C, Laffon A, Blanco F J, Carmona L
Rheumatology Division, Complejo Hospitalario Universitario Juan Canalejo A. Coruña, Spain.
Clin Exp Rheumatol. 2008 Mar-Apr;26(2):324-32.
To estimate the point prevalence of knee pain suggesting osteoarthritis (OA) in the adult Spanish population. Secondary objectives were to examine the distribution of associated factors, as well as to assess the impact of knee pain on quality of life and function in the general population.
A population survey was conducted in year 2000 for which 2,192 subjects over 20 years of age were selected by stratified polystage cluster sampling from the censuses of 20 towns. Trained rheumatologists administered structured interviews that permitted them to rule out the presence of rheumatic symptoms, and which included validated instruments to measure function and quality of life. We used the definition of clinical symptomatic knee OA of the American College of Rheumatology.
The estimated prevalence of knee pain suggesting OA in the general adult population is 10.2% (95% confidence interval: 7.9-12.5). Elderly women with fewer studies and from the lower social class, as well as those subjects involved in physically demanding jobs are more frequently affected. Obesity is also an important determinant for knee pain suggesting OA. Knee pain is associated to a significant decrease in functional ability and quality of life, even after adjustment for age, sex, and comorbidity.
The prevalence of knee pain suggesting OA in the general Spanish population is higher than expected, mainly related to a high rate of knee pain in women over 55. The proportion of very old persons and of those obese are important factors to take into account when comparing the rate of knee OA between populations.
评估西班牙成年人群中提示骨关节炎（OA）的膝关节疼痛的点患病率。次要目的是研究相关因素的分布情况，并评估膝关节疼痛对普通人群生活质量和功能的影响。
2000年开展了一项人群调查，通过分层多阶段整群抽样从20个城镇的人口普查中选取了2192名20岁以上的受试者。经过培训的风湿病学家进行结构化访谈，以排除风湿症状的存在，并使用经过验证的工具来测量功能和生活质量。我们采用了美国风湿病学会临床症状性膝关节OA的定义。
普通成年人群中提示OA的膝关节疼痛的估计患病率为10.2%（95%置信区间：7.9 - 12.5）。受教育程度较低、来自社会阶层较低的老年女性，以及从事体力要求较高工作的人群受影响更为频繁。肥胖也是提示OA的膝关节疼痛的一个重要决定因素。即使在对年龄、性别和合并症进行调整后，膝关节疼痛仍与功能能力和生活质量的显著下降相关。
西班牙普通人群中提示OA的膝关节疼痛的患病率高于预期，主要与55岁以上女性膝关节疼痛的高发生率有关。在比较不同人群的膝关节OA发生率时，高龄人群和肥胖人群的比例是需要考虑的重要因素。
