Azrak Birgül, Callaway Angelika, Willershausen Brita, Ebadi Saeideh, Gleissner Christiane
Department of Restorative Dentistry, Johannes Gutenberg University, Mainz, Germany.
Schweiz Monatsschr Zahnmed. 2008;118(8):702-8.
The aim of this study was to compare the results of a new method, measurement of lactic-acid production on the tongue (LAP), with established methods of caries risk assessment in children.
One hundred nineteen children (6-10 years old) participated in the study. Data collection included number of carious lesions (D-T) and filled teeth (F-T), approximal plaque index (API), LAP, buffering capacity (BC), counts of mutans streptococci (MS) and lactobacilli (LB) in stimulated saliva. According to caries presence, the children were divided into low risk (LR group; D-T = 0) and high risk (HR group; D-T > or = 1) groups. Statistical analysis was performed using Chi-square test, Spearman's test for nonparametric correlations, uni- and multivariate regression analysis.
Seventy-two children (F-T = 0.4 +/- 1.4) were in the LR and 47 (D-T = 2.5 +/- 2.7; F-T = 1.5 +/- 1.9) in the HR group. The correlation analysis verified statistically significant correlations between D-T and the salivary counts of MS/LB and between D-T and F-T. API correlated with F-T and LB, while F-T and LB also correlated with each other significantly. The counts of MS and LB showed also a significant correlation. The LAP showed a significant correlation only to F-T. Significances in univariate regression analysis were found for F-T, counts of LB and MS in saliva, and for LAP. The multivariate regression analysis indicated significances only for F-T and LB in saliva, but not for LAP.
LAP might be useful only as a supplementary screening tool for caries risk assessment, but not as a sole predictor.
本研究旨在比较一种新方法——测量舌部乳酸生成量(LAP)与儿童龋齿风险评估的既定方法的结果。
119名6至10岁儿童参与了本研究。数据收集包括龋损数量(D-T)、补牙数量(F-T)、邻面菌斑指数(API)、LAP、缓冲能力(BC)、刺激唾液中变形链球菌(MS)和乳酸杆菌(LB)的计数。根据是否存在龋齿,儿童被分为低风险组(LR组;D-T = 0)和高风险组(HR组;D-T≥1)。使用卡方检验、Spearman非参数相关性检验、单因素和多因素回归分析进行统计分析。
LR组有72名儿童(F-T = 0.4±1.4),HR组有47名儿童(D-T = 2.5±2.7;F-T = 1.5±1.9)。相关性分析证实D-T与MS/LB的唾液计数之间以及D-T与F-T之间存在统计学显著相关性。API与F-T和LB相关,而F-T和LB之间也显著相关。MS和LB的计数也显示出显著相关性。LAP仅与F-T显示出显著相关性。单因素回归分析发现F-T、唾液中LB和MS的计数以及LAP具有显著性。多因素回归分析仅表明唾液中的F-T和LB具有显著性,而LAP不具有显著性。
LAP可能仅作为龋齿风险评估的辅助筛查工具有用,但不能作为唯一的预测指标。