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具有双酶途径和DNA的电化学生物传感器,用于筛选芳胺的有毒反应性代谢物。

Electrochemical biosensor featuring a two-enzyme pathway and DNA for screening toxic reactive metabolites of arylamines.

作者信息

So Minjeong, Schenkman John B, Rusling James F

机构信息

Department of Chemistry, University of Connecticut, USA.

出版信息

Chem Commun (Camb). 2008 Sep 28(36):4354-6. doi: 10.1039/b805447a. Epub 2008 Jul 18.

Abstract

We demonstrate for the first time a biosensor featuring a sequential two-enzyme pathway suitable to screen potentially toxic reactive metabolites generated during metabolism.

摘要

我们首次展示了一种生物传感器,其具有适合筛选代谢过程中产生的潜在有毒反应性代谢物的连续双酶途径。

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