Wesner R B, Noyes R
Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52240.
J Affect Disord. 1991 May-Jun;22(1-2):43-8. doi: 10.1016/0165-0327(91)90082-4.
Ten subjects with illness phobia were treated with imipramine for 8 weeks. All of the eight subjects who remained on the drug for 4 weeks or more reported at least moderate improvement. Overstimulatory reactions occurred in four subjects causing two to discontinue medication. Imipramine appears to be a potentially useful treatment for this subtype of hypochondriasis.
十名患有疾病恐惧症的受试者接受了为期8周的丙咪嗪治疗。在持续服药4周或更长时间的八名受试者中,所有人都报告至少有中度改善。四名受试者出现过度刺激反应,导致两人停药。丙咪嗪似乎是治疗这种疑病症亚型的一种潜在有效疗法。