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[结膜过敏性肉芽肿性结节揭示盘尾丝虫病]

[Allergic granulomatous nodule of the conjunctiva disclosing onchocerciasis].

作者信息

Basset D, D'Hermies F, Pouliquen Y, Lagrange P H

机构信息

Service de Microbiologie, Hôtel Dieu de Paris, France.

出版信息

J Fr Ophtalmol. 1991;14(2):113-7.

PMID:1880338
Abstract

A new case of conjunctival allergic nodule is reported in a Guinean man. This lesion was first described by Ashton and Cook in 1979. Histologically, this nodule consists of amorphous eosinophilic material surrounded by epithelioid and giant cells arranged in a pallisade; some eosinophils are often found in the inflammatory reaction. This lesion usually resolves spontaneously. In documented cases, nematodes and particularly filaria such as Mansonella perstans are usually isolated. Our observation is the first documented case with Onchocerca volvulus. Microfilariae were detected by examination of normal saline containing the biopsy specimen. The new major antifilarial treatment ivermectin was associated.

摘要

一名几内亚男子被报告患有一例新的结膜过敏性结节。这种病变最早由阿什顿和库克于1979年描述。组织学上,这个结节由无定形嗜酸性物质组成,周围是呈栅栏状排列的上皮样细胞和巨细胞;在炎症反应中经常发现一些嗜酸性粒细胞。这种病变通常会自行消退。在有记录的病例中,通常能分离出线虫,特别是丝虫,如常现曼森线虫。我们的观察是第一例有盘尾丝虫病的记录病例。通过检查含有活检标本的生理盐水检测到了微丝蚴。同时使用了新型主要抗丝虫治疗药物伊维菌素。

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