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Low-frequency electro-acupuncture and physical exercise improve metabolic disturbances and modulate gene expression in adipose tissue in rats with dihydrotestosterone-induced polycystic ovary syndrome.低频电针和体育锻炼可改善二氢睾酮诱导的多囊卵巢综合征大鼠的代谢紊乱并调节脂肪组织中的基因表达。
Endocrinology. 2008 Jul;149(7):3559-68. doi: 10.1210/en.2008-0053. Epub 2008 Apr 3.
2
Acupuncture modulates resting state connectivity in default and sensorimotor brain networks.针刺可调节默认及感觉运动脑网络中的静息态连接。
Pain. 2008 Jun;136(3):407-418. doi: 10.1016/j.pain.2008.01.011. Epub 2008 Mar 11.
3
Acupuncture with in vitro fertilisation.针灸与体外受精
BMJ. 2008 Mar 8;336(7643):517-8. doi: 10.1136/bmj.39503.643727.80.
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Effects of acupuncture on rates of pregnancy and live birth among women undergoing in vitro fertilisation: systematic review and meta-analysis.针灸对接受体外受精女性的妊娠率和活产率的影响:系统评价和荟萃分析
BMJ. 2008 Mar 8;336(7643):545-9. doi: 10.1136/bmj.39471.430451.BE. Epub 2008 Feb 7.
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Electrical properties of acupuncture points and meridians: a systematic review.穴位与经络的电学特性:一项系统综述。
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Biochemicals associated with pain and inflammation are elevated in sites near to and remote from active myofascial trigger points.与疼痛和炎症相关的生化物质在活跃肌筋膜触发点附近及远处的部位都会升高。
Arch Phys Med Rehabil. 2008 Jan;89(1):16-23. doi: 10.1016/j.apmr.2007.10.018.
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Electroacupuncture suppresses hyperalgesia and spinal Fos expression by activating the descending inhibitory system.电针通过激活下行抑制系统来抑制痛觉过敏和脊髓Fos表达。
Brain Res. 2007 Dec;1186:171-9. doi: 10.1016/j.brainres.2007.10.022. Epub 2007 Oct 22.
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Role of medullary GABA, opioids, and nociceptin in prolonged inhibition of cardiovascular sympathoexcitatory reflexes during electroacupuncture in cats.延髓γ-氨基丁酸、阿片类物质和孤啡肽在猫电针期间对心血管交感兴奋反射的长期抑制中的作用。
Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3627-35. doi: 10.1152/ajpheart.00842.2007. Epub 2007 Sep 21.
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Decreased central mu-opioid receptor availability in fibromyalgia.纤维肌痛患者中枢μ-阿片受体可用性降低。
J Neurosci. 2007 Sep 12;27(37):10000-6. doi: 10.1523/JNEUROSCI.2849-07.2007.
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Neuroimaging acupuncture effects in the human brain.神经影像学研究针刺对人脑的影响。
J Altern Complement Med. 2007 Jul-Aug;13(6):603-16. doi: 10.1089/acm.2007.7040.

针灸机制研究的现状与未来

The status and future of acupuncture mechanism research.

作者信息

Napadow Vitaly, Ahn Andrew, Longhurst John, Lao Lixing, Stener-Victorin Elisabet, Harris Richard, Langevin Helene M

机构信息

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charleston, MA 02129, USA.

出版信息

J Altern Complement Med. 2008 Sep;14(7):861-9. doi: 10.1089/acm.2008.SAR-3.

DOI:10.1089/acm.2008.SAR-3
PMID:18803495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3155097/
Abstract

On November 8-9, 2007, the Society for Acupuncture Research (SAR) hosted an international conference to mark the tenth anniversary of the landmark NIH [National Institutes of Health] Consensus Development Conference on Acupuncture. More than 300 acupuncture researchers, practitioners, students, funding agency personnel, and health policy analysts from 20 countries attended the SAR meeting held at the University of Maryland School of Medicine, Baltimore, MD. This paper summarizes important invited lectures in the area of basic and translational acupuncture research. Specific areas include the scientific assessment of acupuncture points and meridians, the neural mechanisms of cardiovascular regulation by acupuncture, mechanisms for electroacupuncture applied to persistent inflammation and pain, basic and translational research on acupuncture in gynecologic applications, the application of functional neuroimaging to acupuncture research with specific application to carpal-tunnel syndrome and fibromyalgia, and the association of the connective tissue system to acupuncture research. In summary, mechanistic models for acupuncture effects that have been investigated experimentally have focused on the effects of acupuncture needle stimulation on the nervous system, muscles, and connective tissue. These mechanistic models are not mutually exclusive. Iterative testing, expanding, and perhaps merging of such models will potentially lead to an incremental understanding of the effects of manual and electrical stimulation of acupuncture needles that is solidly rooted in physiology.

摘要

2007年11月8日至9日,针灸研究学会(SAR)主办了一次国际会议,以纪念具有里程碑意义的美国国立卫生研究院(NIH)针灸共识发展会议十周年。来自20个国家的300多名针灸研究人员、从业者、学生、资助机构人员和卫生政策分析师参加了在马里兰州巴尔的摩市马里兰大学医学院举行的SAR会议。本文总结了基础和转化针灸研究领域的重要特邀讲座。具体领域包括穴位和经络的科学评估、针灸对心血管调节的神经机制、电针治疗持续性炎症和疼痛的机制、针灸在妇科应用中的基础和转化研究、功能神经成像在针灸研究中的应用(特别是针对腕管综合征和纤维肌痛)以及结缔组织系统与针灸研究的关联。总之,通过实验研究的针灸效应机制模型主要集中在针刺刺激对神经系统、肌肉和结缔组织的影响。这些机制模型并非相互排斥。对这些模型进行反复测试、扩展甚至合并,可能会逐步加深我们对基于生理学的手动和电针刺激效应的理解。