Saito M
Aichi Prefectural Institute of Public Health.
Kansenshogaku Zasshi. 1991 May;65(5):571-6. doi: 10.11150/kansenshogakuzasshi1970.65.571.
The excretion in the feces of Clostridium perfringens producing enterotoxin by 48 patients in 3 cases of food poisoning was studied during the illness and 1 and 3 months after the onset. Patients in the first outbreak excreted such strains mostly in the form of spores. In the second outbreak, spores and viable count cells were excreted in nearly equal numbers, and about 50% of the spores were enterotoxigenic. In the third outbreak, the strains were detected both as spores and as viable count cells during the illness. In all three groups, most fecal samples contained at least 10(3) spores per gram. About 1 month after the onset of the illness, (long after recovery from symptoms), 12 colonies producing enterotoxin were detected from five of the 22 samples of feces obtained from subjects in the three groups. There were few C. perfringens organisms, mostly spores, in the feces. Enterotoxin was not detected in the feces. About 3 months after onset, colonies producing enterotoxin could not be detected from feces of 11 of the subjects in the first group. We conclude that persons affected by C. perfringens food poisoning might contaminate food for at least 1 month after the onset.
对48例3起食物中毒事件患者在患病期间以及发病后1个月和3个月时产气荚膜梭菌产肠毒素菌株的粪便排泄情况进行了研究。在首次暴发中，患者排出的此类菌株大多为孢子形式。在第二次暴发中，孢子和活菌计数细胞的排出数量几乎相等，且约50%的孢子具有产肠毒素能力。在第三次暴发中，患病期间检测到的菌株既有孢子形式也有活菌计数细胞形式。在所有三组中，大多数粪便样本每克至少含有10³个孢子。在发病约1个月后（症状恢复很久之后），从三组受试者的22份粪便样本中的5份中检测到12个产肠毒素菌落。粪便中产气荚膜梭菌数量很少，大多为孢子。粪便中未检测到肠毒素。发病约3个月后，第一组11名受试者的粪便中未检测到产肠毒素菌落。我们得出结论，产气荚膜梭菌食物中毒患者在发病后可能至少1个月内都会污染食物。
