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基于生物传感器的过渡金属配合物与DNA相互作用的研究进展及其应用

Recent development of interaction of transition metal complexes with DNA based on biosensor and its applications.

作者信息

Li Feng, Chen Wei, Tang Chenfei, Zhang Shusheng

机构信息

Key Laboratory of Eco-Chemical Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.

出版信息

Talanta. 2008 Oct 19;77(1):1-8. doi: 10.1016/j.talanta.2008.06.011. Epub 2008 Jun 17.

Abstract

In this article interaction of transition metal complexes with DNA and its applications in electrochemical DNA biosensors as hybridization indicator or electroactive marker of DNA are reviewed. Special emphasis has been given to the efforts for the development of new transition metal complexes and their interaction to DNA. DNA and polymers covalently conjugated with transition metal complexes were also reviewed.

摘要

本文综述了过渡金属配合物与DNA的相互作用及其在电化学DNA生物传感器中作为DNA杂交指示剂或电活性标记物的应用。特别强调了开发新型过渡金属配合物及其与DNA相互作用的研究工作。还综述了与过渡金属配合物共价共轭的DNA和聚合物。

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