Tull Matthew T, Stipelman Brooke A, Salters-Pedneault Kristalyn, Gratz Kim L
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS 39216, USA.
J Anxiety Disord. 2009 Mar;23(2):275-82. doi: 10.1016/j.janxdis.2008.08.002. Epub 2008 Aug 12.
Both non-clinical panic attacks and panic disorder (PD) have been found to be associated with generalized anxiety disorder (GAD). This study examined a proxy risk factor model of the relationship between non-clinical panic attacks, PD, and GAD. Specifically, it was proposed that non-clinical panic attacks and PD predict GAD only due to their shared association with anxiety sensitivity (AS) and difficulties in emotion regulation. Results demonstrated that emotion regulation difficulties reliably predicted GAD above and beyond the experience of non-clinical panic attacks and PD. However, although PD lost strength as a predictor, it remained significantly associated with GAD in the full model, providing only partial support for the proposed proxy risk factor model. Findings speak to the underlying role of emotion regulation difficulties in GAD, and suggest that it may be the shared relationship of these difficulties with both PD and GAD that partially explain the association of these disorders.
非临床惊恐发作和惊恐障碍(PD)均被发现与广泛性焦虑障碍(GAD)有关。本研究检验了非临床惊恐发作、PD和GAD之间关系的替代风险因素模型。具体而言,研究提出非临床惊恐发作和PD仅因其与焦虑敏感性(AS)和情绪调节困难的共同关联而预测GAD。结果表明,情绪调节困难能够可靠地预测GAD,且超出了非临床惊恐发作和PD的体验。然而,尽管PD作为预测因素的强度有所下降,但在完整模型中它仍与GAD显著相关,仅为所提出的替代风险因素模型提供了部分支持。研究结果揭示了情绪调节困难在GAD中的潜在作用,并表明可能正是这些困难与PD和GAD的共同关系部分解释了这些障碍之间的关联。