Buchman Joshua J, Tsai Li-Huei
Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Cell. 2008 Sep 19;134(6):912-4. doi: 10.1016/j.cell.2008.09.007.
The nuclei of progenitor cells in developing neural epithelia change their position during the cell cycle through a process called interkinetic nuclear migration. Del Bene et al. (2008) report that defects in the machinery controlling this process lead to altered exposure to Notch signals and systemic effects on neurogenesis in the retina.
在发育中的神经上皮中，祖细胞的细胞核在细胞周期中通过一种称为动核间迁移的过程改变其位置。德尔·贝内等人（2008年）报告称，控制这一过程的机制缺陷会导致Notch信号的暴露改变，并对视网膜神经发生产生系统性影响。
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