慢性肾病患者外周动脉疾病的流行病学与诊断

Epidemiology and diagnosis of peripheral arterial disease in patients with chronic kidney disease.

作者信息

Ix Joachim H, Criqui Michael H

机构信息

Department of Medicine, Division of Nephrology and Hypertension, University of California San Diego, San Diego, CA 92161, USA.

出版信息

Adv Chronic Kidney Dis. 2008 Oct;15(4):378-83. doi: 10.1053/j.ackd.2008.07.007.

DOI:10.1053/j.ackd.2008.07.007

PMID:18805384

Abstract

Chronic kidney disease (CKD) and peripheral arterial disease (PAD) are common and frequently coexist. Among subjects with CKD, arterial disease may be due to atherosclerosis, medial arterial calcification (MAC), or both conditions concomitantly. It is important for clinicians to recognize both conditions because each identifies individuals at higher risk of cardiovascular disease events, and because the presence of MAC complicates interpretation of the ankle brachial index, the most commonly used diagnostic test for artherosclerotic PAD. To that end, we review the epidemiology and diagnosis of atherosclerotic PAD and medical arterial calcification in patients with CKD.

摘要

慢性肾脏病（CKD）和外周动脉疾病（PAD）很常见且常同时存在。在CKD患者中，动脉疾病可能是由动脉粥样硬化、动脉中层钙化（MAC）或这两种情况共同导致的。临床医生认识到这两种情况很重要，因为它们各自都表明个体发生心血管疾病事件的风险更高，还因为MAC的存在会使踝肱指数（用于诊断动脉粥样硬化性PAD的最常用检测方法）的解读变得复杂。为此，我们回顾了CKD患者中动脉粥样硬化性PAD和医源性动脉钙化的流行病学及诊断情况。