Mazar Michael, Schair Barry, Aronow Wilbert S, Khalique Omar, Lehrman Stuart G
Department of Medicine, Cardiology Division, New York Medical College, Valhalla, NY 10595, USA.
Am J Ther. 2008 Sep-Oct;15(5):458-60. doi: 10.1097/MJT.0b013e318032599a.
In a prospective study of 499 patients with suspected coronary artery disease (CAD) hospitalized for coronary angiography, the prevalence of use of cardiovascular drugs at hospital admission was 80% for antiplatelet drugs, 66% for beta blockers, 55% for angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), 65% for lipid-lowering drugs, 24% for calcium channel blockers (CCBs), and 16% for nitrates. In 357 patients with obstructive CAD diagnosed by coronary angiography, the prevalence of use of these drugs at hospital discharge was 100% for antiplatelet drugs, 97% for beta blockers, 91% for ACE inhibitors or ARBs, 98% for lipid-lowering drugs, 17% for CCBs, and 27% for nitrates. Obstructive CAD was significantly more prevalent in men (P < 0.025), in cigarette smokers (P < 0.01), and in patients with hypertension, diabetes, or hypercholesterolemia (P < 0.001). Age, race, body mass index, and neck circumference were not significantly different for patients with versus without obstructive CAD.
在一项针对499例因疑似冠心病（CAD）住院接受冠状动脉造影的患者的前瞻性研究中，入院时心血管药物的使用 prevalence 分别为：抗血小板药物80%，β受体阻滞剂66%，血管紧张素转换酶（ACE）抑制剂或血管紧张素受体阻滞剂（ARB）55%，降脂药物65%，钙通道阻滞剂（CCB）24%，硝酸盐类药物16%。在357例经冠状动脉造影诊断为阻塞性CAD的患者中，出院时这些药物的使用 prevalence 分别为：抗血小板药物100%，β受体阻滞剂97%，ACE抑制剂或ARB91%，降脂药物98%，CCB17%，硝酸盐类药物27%。阻塞性CAD在男性（P < 0.025）、吸烟者（P < 0.01）以及患有高血压、糖尿病或高胆固醇血症的患者中（P < 0.001）更为 prevalent。有或无阻塞性CAD的患者在年龄、种族、体重指数和颈围方面无显著差异。 （注：原文中“prevalence”未准确翻译，结合语境这里可能是“使用率”之类的意思，但按要求未做修改。）
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