用于生物组织应用的两种简单漫反射模型的比较评估。

Comparative evaluation of two simple diffuse reflectance models for biological tissue applications.

作者信息

Zonios George, Bassukas Ioannis, Dimou Aikaterini

机构信息

Department of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.

出版信息

Appl Opt. 2008 Sep 20;47(27):4965-73. doi: 10.1364/ao.47.004965.

DOI:10.1364/ao.47.004965

PMID:18806859

Abstract

We present a comparative evaluation of two simple diffuse reflectance models for biological tissue applications. One model is based on a widely accepted and used in biomedical optics implementation of diffusion theory, and the other one is based on a semiempirical approach derived from basic physical principles. We test the models on tissue phantoms and on human skin, utilizing a standard six-around-one optical fiber probe for light delivery and collection. We show that both models are suitable for use with an optical fiber probe and illustrate the potential, applicability, and validity range of the models.

摘要

我们对两种用于生物组织应用的简单漫反射模型进行了比较评估。一种模型基于扩散理论在生物医学光学中的广泛接受和应用，另一种基于从基本物理原理推导出来的半经验方法。我们使用标准的六环一光纤探头进行光传输和收集，在组织模型和人体皮肤上对模型进行测试。我们表明这两种模型都适用于光纤探头，并说明了模型的潜力、适用性和有效范围。