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[暴发性心肌炎43个月后猝死及非伤寒沙门菌病中的双峰性肌炎]

[Sudden cardiac death 43 months after fulminant myocarditis and two-peaked myositis in non-typhoid salmonellosis].

作者信息

Hammerer Matthias, Altenberger Johann, Pichler Maximilian

机构信息

Universitätsklinik für Innere Medizin II, Kardiologie und Internistische Intensivmedizin, Paracelsus Medizinische Privatuniversität Salzburg, Salzburg, Osterreich.

出版信息

Wien Med Wochenschr. 2008;158(17-18):509-17. doi: 10.1007/s10354-008-0573-4.

Abstract

HISTORY AND CLINICAL FINDINGS

A previously healthy 29-year-old male was hospitalized due to acute myalgia and high temperature following an uncomplicated gastroenteritis. Within 24 hours, he developed life-threatening hemodynamic shock with the need for inotropic support and sustained ventricular tachycardia.

INVESTIGATIONS

Echocardiography and electrocardiogram as well as lab tests were consistent with the diagnosis of fulminant myocarditis and acute myositis. Serological and bacteriological analysis yielded an acute infection with salmonella D.

TREATMENT AND COURSE

The patient's condition stabilized under conservative supportive care within a few days. Apart from a histologically confirmed recurrent myositis four weeks later, no further complications occurred and the patient was clinically and echocardiographically considered to be in complete functional remission. Three and a half years later, however, the patient unexpectedly and suddenly died.

CONCLUSIONS

Although fulminant myocarditis is a life-threatening condition in its initial phase, the prognosis after recovery is considered to be good. However, this case study suggests that sudden cardiac death as a late complication of fulminant myocarditis may occur.

摘要

病史与临床发现

一名既往健康的29岁男性因单纯性肠胃炎后出现急性肌痛和高热而住院。在24小时内,他发展为危及生命的血流动力学休克,需要使用血管活性药物支持,且出现持续性室性心动过速。

检查

超声心动图、心电图以及实验室检查结果均符合暴发性心肌炎和急性肌炎的诊断。血清学和细菌学分析显示为D组沙门氏菌急性感染。

治疗与病程

患者病情在数天的保守支持治疗下趋于稳定。除四周后组织学确诊复发性肌炎外,未出现进一步并发症,临床和超声心动图检查认为患者已完全恢复功能。然而,三年半后,患者意外突然死亡。

结论

尽管暴发性心肌炎在初始阶段是危及生命的疾病,但恢复后的预后被认为良好。然而,本病例研究提示暴发性心肌炎的晚期并发症可能会发生心源性猝死。

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