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[膝关节持续性炎性关节炎的局部治疗:关节腔内注射糖皮质激素及卧床休息]

[Local treatment for persistent inflammatory arthritis of the knee: intra-articular injection of glucocorticoids and bed rest].

作者信息

Bijlsma J W J, Saris D B F, Jahangier Z N

机构信息

Universitair Medisch Centrum Utrecht, Utrecht.

出版信息

Ned Tijdschr Geneeskd. 2008 Sep 6;152(36):1956-8.

Abstract

Two studies evaluating treatment options for persistent mono-arthritis are discussed. In one study arthroscopic lavage plus intra-articular glucocorticoids was compared with arthroscopic lavage without glucocorticoids, and with joint aspiration plus glucocorticoids. Both intra-articular glucocorticoids and lavage have their merits, but glucocorticoids appear to be slightly more effective. In the second study radioactive Yttrium plus intra-articular glucocorticoids was compared with glucocorticoids alone. Yttrium provided little additional value. There are some indications that a period of strict bed rest after treatment is beneficial. Intra-articular glucocorticoids should not be administered more frequently than three times per year in the same joint.

摘要

本文讨论了两项评估持续性单关节炎治疗方案的研究。在一项研究中,对关节镜灌洗联合关节内注射糖皮质激素、单纯关节镜灌洗以及关节穿刺联合糖皮质激素进行了比较。关节内注射糖皮质激素和灌洗都有各自的优点,但糖皮质激素似乎效果稍好。在第二项研究中,对放射性钇联合关节内注射糖皮质激素与单纯使用糖皮质激素进行了比较。钇几乎没有额外的价值。有一些迹象表明治疗后一段时间的严格卧床休息是有益的。同一关节内注射糖皮质激素每年不应超过三次。

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