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前来接受减肥手术评估的病态肥胖患者中睡眠呼吸暂停的患病率:为减肥手术前常规筛查阻塞性睡眠呼吸暂停提供更多证据。

Prevalence of sleep apnea in morbidly obese patients who presented for weight loss surgery evaluation: more evidence for routine screening for obstructive sleep apnea before weight loss surgery.

作者信息

Lopez Peter P, Stefan Bianca, Schulman Carl I, Byers Patricia M

机构信息

Department of Surgery, University of Texas Health Science Center-San Antonio, San Antonio, Texas 78229, USA.

出版信息

Am Surg. 2008 Sep;74(9):834-8.

Abstract

The incidence of obstructive sleep apnea has been underestimated in morbidly obese patients who present for evaluation for weight loss surgery. This retrospective study shows that the incidence of obstructive sleep apnea in this patient population is greater than 70 per cent and increases in incidence as the body mass index increases. Obstructive sleep apnea (OSA) is a common comorbidity in obese patients who present for evaluation for gastric bypass surgery. The incidence of sleep apnea in obese patients has been reported to be as high as 40 per cent. A retrospective review of our prospectively collected database was performed. All patients being evaluated for weight loss surgery for obesity were screened preoperatively for OSA using a sleep study. The overall incidence of sleep apnea in our patients was 78 per cent (227 of 290). All 227 were diagnosed by formal sleep study. There were 63 (22%) males and 227 (78%) females. The mean age was 43 years (range, 17-75 years). The mean body mass index (BMI) was 52 kg/m2 (range, 31-94 kg/m2). The prevalence of OSA in the severely obese group (BMI 35-39.9 kg/m2) was 71 per cent. For the morbidly obese group (BMI 40-40.9 kg/m2), the prevalence was 74 per cent and for the superobese group (BMI 50-59.9 kg/m2) 77 per cent. Those with a BMI 60 kg/m2 or greater, the prevalence of OSA rose to 95 per cent. The incidence of sleep apnea in patients presenting for weight loss surgery was greater than 70 per cent in our study. Patients presenting for weight loss surgery should undergo a formal sleep study to diagnose OSA before bariatric surgery.

摘要

在因减重手术前来评估的病态肥胖患者中,阻塞性睡眠呼吸暂停的发病率一直被低估。这项回顾性研究表明,该患者群体中阻塞性睡眠呼吸暂停的发病率超过70%,且随着体重指数的增加而上升。阻塞性睡眠呼吸暂停(OSA)是因胃旁路手术前来评估的肥胖患者中常见的合并症。据报道,肥胖患者中睡眠呼吸暂停的发病率高达40%。我们对前瞻性收集的数据库进行了回顾性分析。所有因肥胖接受减重手术评估的患者术前均通过睡眠研究筛查OSA。我们患者中睡眠呼吸暂停的总体发病率为78%(290例中有227例)。所有227例均通过正式的睡眠研究确诊。其中男性63例(22%),女性227例(78%)。平均年龄为43岁(范围17 - 75岁)。平均体重指数(BMI)为52 kg/m²(范围31 - 94 kg/m²)。重度肥胖组(BMI 35 - 39.9 kg/m²)中OSA的患病率为71%。病态肥胖组(BMI 40 - 49.9 kg/m²)的患病率为74%,超级肥胖组(BMI 50 - 59.9 kg/m²)为77%。BMI 60 kg/m²及以上者,OSA的患病率升至95%。在我们的研究中,因减重手术前来就诊的患者中睡眠呼吸暂停的发病率超过70%。因减重手术前来就诊的患者在进行减肥手术前应接受正式的睡眠研究以诊断OSA。

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