Martelli Vanessa, Doumouras Aristithes G, Mbuagbaw Lawrence, Ayas Najib, Tarride Jean-Eric
Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON, Canada.
Division of Respirology and Sleep Medicine, Department of Medicine, Queen's University, Kingston, ON, Canada.
Sleep Breath. 2025 Jan 16;29(1):80. doi: 10.1007/s11325-025-03246-x.
A high proportion of obstructive sleep apnea (OSA) remains undiagnosed. The main objectives of this study were to measure the prevalence of diagnosed OSA and determine OSA predictors in patients who underwent bariatric surgery, who are predominantly female and pre-menopausal and represent an understudied population in OSA literature.
This was a cross-sectional population-based study using the Ontario Bariatric Registry (OBR) from 2010 to 2016, linked to ICES databases which include health administrative data on all encounters within a single public-payer system. Multiple logistic regression was used to measure OSA predictors.
Out of a total of 18,074 patients who underwent bariatric surgery, OSA was diagnosed in 47% (95% confidence interval [CI]: 46 to 47), and OSA was the second most common comorbidity within this population. Only 63% of OSA diagnoses were recorded in the OBR at the time of initial bariatric consultation. Based on interaction, it was found that, in females, OSA predictors included social inequality, diabetes and chronic obstructive pulmonary disease, in addition to the predictors measured in males (age, body mass index and comorbidity burden).
A significant proportion of patients presenting for initial bariatric surgery consultation have undiagnosed OSA. OSA screening and testing may lead to underdiagnosis of OSA, especially in pre-menopausal females who represent the majority of the population undergoing bariatric surgery.
相当一部分阻塞性睡眠呼吸暂停(OSA)仍未得到诊断。本研究的主要目的是测量已确诊OSA的患病率,并确定接受减肥手术患者的OSA预测因素,这些患者以绝经前女性为主,是OSA文献中研究较少的人群。
这是一项基于人群的横断面研究,使用了2010年至2016年的安大略减肥登记处(OBR),并与ICES数据库相链接,该数据库包括单一公共支付系统内所有就诊的健康管理数据。采用多元逻辑回归来测量OSA预测因素。
在总共18074例接受减肥手术的患者中,47%(95%置信区间[CI]:46至47)被诊断为OSA,OSA是该人群中第二常见的合并症。在初次减肥咨询时,OBR中仅记录了63%的OSA诊断。基于交互作用发现,在女性中,除了在男性中测量的预测因素(年龄、体重指数和合并症负担)外,OSA预测因素还包括社会不平等、糖尿病和慢性阻塞性肺疾病。
相当一部分前来进行初次减肥手术咨询的患者存在未被诊断的OSA。OSA筛查和检测可能导致OSA诊断不足,尤其是在占减肥手术人群大多数的绝经前女性中。