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[一氧化氮对穴位与经络去甲肾上腺素能功能及皮肤电阻的影响]

[Effect of nitric oxide on noradrenergic function and skin electric resistance of acupoints and meridians].

作者信息

Liang Yuan, Ma Sheng-Xing, Chen Jia-Xu

机构信息

School of Fundamental Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China.

出版信息

Zhen Ci Yan Jiu. 2008 Jun;33(3):213-6.

PMID:18807729
Abstract

Most acupuncture points correspond to low skin-resistance points (LSRP) on the body surface along the meridians. We did three experiments which conformed that the skin nitric oxide (NO) concentration and expression of neuronal nitric oxide synthesis (nNOS) were higher than those in non-acupoints, and non-meridian control points. Noradrenaline (NE) synthesis/release was modulated by exogenous NO donor and selective inhibitor of nNOS in the skin acupoints/meridians. Skin electrical currents in low skin resistance points were modified by L-arginine-derived NO synthesis and NE. As a conclusion, NO-NE contribute to low resistance characteristics of acupoints and meridians.

摘要

大多数穴位对应于沿经络体表的低皮肤电阻点(LSRP)。我们进行了三项实验,结果证实皮肤一氧化氮(NO)浓度和神经元型一氧化氮合酶(nNOS)的表达高于非穴位和非经络对照点。去甲肾上腺素(NE)的合成/释放受到皮肤穴位/经络中外源性NO供体和nNOS选择性抑制剂的调节。L-精氨酸衍生的NO合成和NE改变了低皮肤电阻点的皮肤电流。总之,NO-NE促成了穴位和经络的低电阻特性。

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