Woods G T, Mansfield M E
Res Commun Chem Pathol Pharmacol. 1976 Dec;15(4):787-95.
Inactivated swine influenza virus was concentrated by filtration. Two 5 ml doses given subcutaneously two to three weeks apart to SPF gilts of breeding age of bred gilts was antigenic as measured by the hemagglutination-inhibition (HI) test. Higher HI titers of longer duration were produced in unvaccinated gilts after experimental challenge. Vaccinated gilts reverted to negative (less than 1:20) HI tests after challenge. Pigs from vaccinated gilts were heavier when weaned at five weeks of age than pigs from unvaccinated gilts. No swine influenza virus was isolated after challenge from placentas or pigs born dead or that died after farrowing.
灭活猪流感病毒通过过滤进行浓缩。对处于繁殖年龄的无特定病原体（SPF）后备母猪，每隔两到三周皮下注射两剂5毫升，通过血凝抑制（HI）试验测定，该疫苗具有抗原性。实验性攻毒后，未接种疫苗的后备母猪产生了更高且持续时间更长的HI效价。接种疫苗的后备母猪在攻毒后HI试验结果恢复为阴性（小于1:20）。五周龄断奶时，接种疫苗的后备母猪所产仔猪比未接种疫苗的后备母猪所产仔猪体重更重。攻毒后，从胎盘或死产或产后死亡的仔猪中未分离到猪流感病毒。
