Laplane D, Orgogozo J M, Meininger V, Degos J D
Rev Neurol (Paris). 1976 Oct;132(10):725-34.
As a result of 6 cases of frontal tumour presenting central facial paralysis with inverse dissociation this symptom was investigated in patients subjected to cortical excisions for intractable epielpsy. A study of 8 cases of frontal cortical excision, 6 of them affecting the internal and posterior portion, and two the prefrontal region, has provided evidence of a link between inverse automatic-voluntary dissociation facial paralysis and lesions affecting the Penfield supplementary motor area. In such cases, facial palsy is usually associated with motor disorders in the limbs, the most characteristic of which is unilateral motor under-utilisation. The possibility of inverse dissociated facial paralysis occurring as a result of a rostral premotor lesion cannot be ruled out in our present state of knowledge.
由于6例额叶肿瘤出现中枢性面瘫并伴有逆向分离，因此对因顽固性癫痫接受皮质切除术的患者的这一症状进行了研究。对8例额叶皮质切除术病例的研究（其中6例影响内后部，2例影响前额叶区域）提供了证据，表明逆向自动-随意分离性面瘫与影响彭菲尔德辅助运动区的病变之间存在联系。在这种情况下，面瘫通常与肢体运动障碍相关，其中最典型的是单侧运动功能未充分利用。就我们目前的认知水平而言，不能排除由于额叶前运动区病变导致逆向分离性面瘫的可能性。
