Tan Glenn Wei Leong, Chia Kok Hoong
Vascular Surgery Service, Department of General Surgery, Tan Tock Seng Hospital, Singapore.
Ann Vasc Surg. 2009 Mar;23(2):256.e13-8. doi: 10.1016/j.avsg.2008.08.014. Epub 2008 Sep 21.
Leiomyosarcoma of primary vascular origin is a rare primary soft tissue tumour, which arises mainly from the inferior vena cava (IVC). Clinical symptoms depend upon the size and location of the tumour and presents usually with abdominal pain, palpable mass and weight loss. Complete surgical resection with clear surgical margin plays a central therapeutic role. The effect of chemotherapy and radiation therapy remains to be evaluated. We report a 64 year old Chinese female who presented with abdominal mass and pain associated with weight loss and was subsequently diagnosed with inferior vena cava leiomyosarcoma. She underwent successful surgical resection but unfortunately developed recurrence of tumour 12 month post-operative. She was also found to have a duplicated inferior vena cave which allowed reconstitution of venous return from the lower limbs after surgical resection of the IVC tumour. We discuss the surgical treatment and results of leiomyosarcoma of the IVC.
原发性血管源性平滑肌肉瘤是一种罕见的原发性软组织肿瘤，主要起源于下腔静脉（IVC）。临床症状取决于肿瘤的大小和位置，通常表现为腹痛、可触及的肿块和体重减轻。完整的手术切除且手术切缘清晰起着核心治疗作用。化疗和放疗的效果仍有待评估。我们报告一名64岁的中国女性，她因腹部肿块、疼痛伴体重减轻就诊，随后被诊断为下腔静脉平滑肌肉瘤。她接受了成功的手术切除，但不幸的是术后12个月肿瘤复发。还发现她有一条重复的下腔静脉，这使得在手术切除IVC肿瘤后下肢静脉回流得以重建。我们讨论了IVC平滑肌肉瘤的手术治疗及结果。
