Bar-On Elhanan, Horesh Zvi, Katz Kalman, Weigl Daniel Martin, Becker Tali, Cleper Rosana, Krause Irit, Davidovits Miriam
Schneider Children's Medical Center, Petah Tikva, Israel.
J Pediatr Orthop. 2008 Oct-Nov;28(7):747-51. doi: 10.1097/BPO.0b013e318186eb99.
Children with renal osteodystrophy (ROD) may develop severe angular deformities of the limbs. Various methods, both medical and surgical, have been described for correction of these deformities, but a literature search showed only 1 child previously treated by the Ilizarov method. The purpose of this study was to characterize the deformities found in our group of patients and to describe our experience in treating these patients with the Ilizarov method.
Correction of angular deformity by the Ilizarov method was performed on 8 limb segments in 5 patients with ROD. Mean age was 14.9 years. Two patients were on hemodialysis, and 3 had functioning kidney grafts. Surgery was deferred until stabilization of metabolic parameters.
There was 1 varus and 7 valgus deformities. Preoperative coronal deformity averaged 29 degrees (18-38 degrees). The Ilizarov apparatus was used in all cases. Correction time averaged 23 days (20-28 days). The time from completion of correction to frame removal averaged 71 days (48-113 days). There were no changes in metabolic parameters or frequency of hemodialysis throughout the treatment. Restoration of a normal mechanical axis was achieved in 4 of the 5 patients. One case failed due to intraarticular instability. There were no major complications. Minor complications included pin tract infections, which responded to antibiotic treatment, and premature consolidation in 1 case. Follow-up averaged 6.5 years (1-10 years). The alignment obtained at surgery was maintained in all 4 patients, and they are functional and symptom-free. The patient for whom the surgery failed remains wheelchair-bound.
The Ilizarov method was found to be safe and effective for correction of malalignment due to ROD. Optimization of metabolic parameters is essential before surgery and throughout correction. The procedure is contraindicated in patients with significant intraarticular knee pathology.
患有肾性骨营养不良(ROD)的儿童可能会出现严重的肢体角畸形。已经描述了多种用于矫正这些畸形的医学和手术方法,但文献检索显示之前仅有1例儿童接受过伊里扎洛夫方法治疗。本研究的目的是描述我们这组患者中发现的畸形特征,并阐述我们使用伊里扎洛夫方法治疗这些患者的经验。
对5例ROD患者的8个肢体节段采用伊里扎洛夫方法矫正角畸形。平均年龄为14.9岁。2例患者接受血液透析,3例有功能正常的肾移植。手术推迟至代谢参数稳定后进行。
有1例内翻畸形和7例外翻畸形。术前冠状面畸形平均为29度(18 - 38度)。所有病例均使用了伊里扎洛夫器械。矫正时间平均为23天(20 - 28天)。从矫正完成到拆除框架的时间平均为71天(48 - 113天)。整个治疗过程中代谢参数和血液透析频率均无变化。5例患者中有4例实现了正常机械轴的恢复。1例因关节内不稳定而失败。无重大并发症。轻微并发症包括针道感染,经抗生素治疗有效,以及1例过早骨愈合。随访平均6.5年(1 - 10年)。手术获得的对线在所有4例患者中均得以维持,他们功能正常且无症状。手术失败的患者仍需依赖轮椅。
发现伊里扎洛夫方法对于矫正ROD所致的对线不良是安全有效的。术前及整个矫正过程中优化代谢参数至关重要。该手术对于有明显膝关节内病变的患者是禁忌的。