Schulman J A, Weight F F
Science. 1976 Dec 24;194(4272):1437-9. doi: 10.1126/science.188131.
Slow decreases of ionic conductance across neuronal cell membranes, which generate slow synaptic potentials, can increase the effectiveness of synaptic transmission. Slow conductance decreases sufficient magnitude increase the amplitude of monosynaptic fast excitatory postsynaptic potentials in B cells of the bullfrog sympathetic ganglion. By this postsynaptic mechanism, activation of one synaptic pathway can cause an increase in transmission, lasting several minutes, across another synapse. This may provide an important mechanism for synaptic integration and control of neuronal interaction.
神经元细胞膜上离子电导的缓慢降低会产生缓慢的突触电位，这能够提高突触传递的效率。足够大幅度的缓慢电导降低会增加牛蛙交感神经节B细胞中单突触快速兴奋性突触后电位的幅度。通过这种突触后机制，一条突触通路的激活可导致另一条突触的传递增强，持续数分钟。这可能为突触整合及神经元相互作用的控制提供了一种重要机制。
